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Severe rheumatoid arthritis
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Ebook "Studies on arthritis and joint disorders" will also provide specific coverage on emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents and several more relevant aspects. In addition, the book will promote the concept of using biomarkers representative of oxidative stress reactions and free radical damage , as well as describe the effect of antioxidants in treating disease in clinical trials.
411p
manmanthanhla0201
26-02-2024
1
1
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Felty syndrome is defined by three conditions: neutropenia, rheumatoid arthritis, and splenomegaly. Neutropenia associated with pancytopenia may further affect the dental condition of a patient. Periodontal treatment and surgery in patients with Felty syndrome necessitates cooperation with a hematologist.
7p
videadpool
05-05-2023
3
2
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This paper has reviewed the scope and causation of sub-optimal compliance, and evaluated improvement strategies and exploration of a best-practice benchmark. As a whole, the results of this study are expected to provide reference for clinical medical professionals.
19p
nguaconbaynhay12
08-06-2021
20
1
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PA28γ (also known as Ki, REG gamma, PMSE3), a member of the ubiquitin-and ATP-independent proteasome activator family 11S, has been proved to show proteasome-dependent and -independent effects on several proteins including tumor suppressor p53, cyclin-dependent kinase inhibitor p21 and steroid receptor co-activator 3 (SCR-3).
10p
viannito2711
20-04-2021
8
1
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While arthrodesis is the standard treatment of a severely arthritic ankle joint, total ankle arthroplasty has become a popular alternative. This review provides clinical outcomes and complications of both interventions in patients with rheumatoid arthritis.
12p
vianrose2711
26-04-2021
9
1
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Patients with rheumatic diseases have a high risk for joint destruction and secondary osteoarthritis (OA) as well as low bone mineral density (BMD, i.e., osteoporosis). While several factors may lead to low BMD in these patients, the value of BMD measurements in rheumatic patients with end-stage OA scheduled for total joint arthroplasty is unknown.
9p
vianttinic2711
20-04-2021
13
2
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CD248 or Endosialin is a transmembrane molecule expressed in stromal cells binding to extracellular matrix (ECM) components. It has been previously implicated in kidney fibrosis, rheumatoid arthritis as well as in tumour-stromal interactions.
10p
vimaine2711
26-03-2021
7
1
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Interstitial lung disease (ILD) is a severe systemic manifestation of rheumatoid arthritis (RA). Highresolution computed tomography (HRCT) represents the gold standard for the diagnosis of ILD, but its routine use for screening programs is not advisable because of both high cost and X-ray exposure.
6p
vimaine2711
26-03-2021
9
2
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Dipeptidyl peptidase-IV (DPP-IV) is suggested to contribute to the pathogenesis of several autoimmune diseases. The aim of this study was to evaluate the association of DPP-IV presence in blood plasma and mononuclear cells with the disease activity in rheumatoid arthritis (RA).
7p
vioregon2711
22-02-2021
10
1
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Peptidylarginine deiminase type 4 (PADI4) has been identified as a susceptibility gene for rheumatoid arthritis (RA) by genome-wide association studies. PADI4 is highly expressed in the bone marrow, macrophages, neutrophils, and monocytes.
15p
vioregon2711
22-02-2021
7
2
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The aim of this retrospective study is to evaluate distal resection interposition arthroplasty of the wrist as a tool to restore mobility as well as to restore stability in severely destroyed wrist joints.
7p
vitennessee2711
01-02-2021
6
2
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The wrist is often severely affected in rheumatoid arthritis (RA) patients; however, little is known about the potential risk factors of the reduced wrist range of motion. In this study, we explored a broad range of possible risk factors of wrist range of motion in RA patients.
8p
vitennessee2711
01-02-2021
6
2
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Rheumatoid Factors (RF) are antibodies directed against the Fc portion of IgG and are involved in clearance of immune complexes. While RF can develop in a wide range of conditions, higher RF levels indicate a greater risk for a severe disease course in Rheumatoid Arthritis (RA) patients including cardiovascular complications and premature death.
5p
vitennessee2711
02-02-2021
8
2
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This study evaluated the effect of early anti-tumor necrosis factor (TNF) therapy in patients with severe rheumatoid arthritis (RA) on the subsequent risk of total knee replacement (TKR) surgery.
5p
vitennessee2711
02-02-2021
5
1
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Foot involvement in rheumatoid arthritis (RA) patients has been reported to severely affect functional capacity and quality of life. We aimed to determine the impact of midfoot and hindfoot involvement on functional disability in Korean patients with RA.
8p
vitennessee2711
02-02-2021
8
2
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Cartilage damage is a crucial feature involved in several pathological conditions characterized by joint disorders, such as osteoarthritis and rheumatoid arthritis. Accumulated evidences showed that Wnt/β-catenin pathway plays a role in the pathogenesis of cartilage damage.
13p
vicolorado2711
23-10-2020
9
1
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Felty’s syndrome (FS) is characterized by the triad of rheumatoid arthritis (RA), splenomegaly and neutropenia. The arthritis is typically severe and virtually always associated with high-titer rheumatoid factor. The presence of persistent neutropenia is generally required to make the diagnosis.
7p
viorochimaru2711
29-05-2020
2
1
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Paracetamol is an analgesic-antipyretic drug and Ibuprofen is a non-steroidal anti-infammatory drug. They are coformulated as tablets to improve analgesia, to simplify prescribing and to improve patient compliance. Three accurate, simple and sensitive spectrophotometric methods were developed for the simultaneous determination of Paraceta‑ mol and Ibuprofen in their co-formulated dosage form.
8p
vijiraiya2711
27-05-2020
20
2
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Abatacept (ABA) is a fusion receptor protein containing the CTLA-4 domain that prevents the activation of naïve T cells by binding the CD80 and CD86 molecules expressed on the surface of dendritic cells, indicated for the treatment of moderate to severe rheumatoid arthritis (RA).
3p
vienzym2711
30-03-2020
15
2
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Rheumatoid arthritis (RA) is a common autoimmune disorder that affects around 1% of the world’s population. The associating morbidity extends out of the joints to involve many vital organs in addition to increased mortality rates. Environmental infections are one of the accused elements to be a risk factor for RA. The relationship between RA and toxoplasmosis was a point of controversy where most of the human studies reported either absent or positive correlation.
11p
quenchua2
16-12-2019
16
0
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