SOS pathway

There has been great progress in ureteral surgery in the last twenty years. The predominant indication is still calculous obstruction but reparative and plastic surgery of the ureter for congenital and acquired lesions are among the most interesting advances in modern urology. The essential goal of this surgery is to ensure free flow of the urine from the kidney to the bladder and so to preserve or improve kidney function which is always affected or threatened by any defect in the excretory pathway.

348p vimeyers 29-05-2024 4 2   Download

Ebook "Botrytis: Biology, pathology and control" is the result of intensive work of 43 authors, all of whom are leading scientists in the Botrytis sciences. Each chapter describes a particular aspect of fungal biology and its impact on disease processes and host response. New technologies have arisen that when applied to long-standing problems or to test new hypotheses have been most rewarding and many of these are covered in this book.

412p cotieubac1004 15-03-2024 3 0   Download

Ebook "Cardiac cytoarchitecture: How to maintain a working heart" presents a collection of expert reviews on different subcellular compartments of the cardiomyocyte, addressing fundamental questions such as how these compartments are assembled during development, how they are changed in and by disease and which signaling pathways have been implicated in these processes so far.

320p manmanthanhla0201 26-02-2024 5 1   Download

Insulin-like growth factor binding proteins (IGFBPs) are critical regulators of the biological activities of insulin-like growth factors. The IGFBP family plays diverse roles in different types of cancer, which we still lack comprehensive and pleiotropic understanding so far.

31p vischultz 20-10-2023 4 1   Download

Ebook "Vehicle maintenance: Vehicle fitting units level 1 and 2" is your introduction to the varied and exciting world of automobiles. It aims to steer you on the pathway to success. This book guides you through many of the practical jobs you will have to do, but vitally helps you to look after your own health and safety. Where necessary, it also gives the basic theory – so you can understand the reasons why.

145p dangsovu 20-10-2023 7 3   Download

PVT1, a previously uncharacterized lncRNA, was identified as a critical regulator involved in multiple functions in tumor, including cell proliferation, cell motility, angiogenesis and so on. However, the clinical significance and underlying mechanism of PVT1 was not be fully explored in glioma.

12p visharma 20-10-2023 4 2   Download

While underlying mechanisms and pathways of social inequalities in cancer survival have been extensively examined in adults, this is less so for children with cancer. Hypothesized mechanisms include prediagnostic utilization of and navigation through the health care system, which may differ by socioeconomic resources of the families.

15p vimahuateng 26-11-2021 9 1   Download

The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus and in vitro validation. Here, we perform whole transcriptome sequencing from Vibrio cholerae treated with mitomycin C as an SOS inducer to characterize the SOS regulon and other pathways affected by this treatment.

18p vibeauty 23-10-2021 11 0   Download

Chitosan (CTS), a natural polysaccharide, exhibits multiple functions of stress adaptation regulation in plants. However, effects and mechanism of CTS on alleviating salt stress damage are still not fully understood.

15p vijichea2711 28-05-2021 11 1   Download

Intercropping is often used in the tea producing areas where land resources are not so abundant, and the produced green tea is tasted more delicious through a tea-Chinese chestnut intercropping system according to the experience of indigenous farmers.

17p vijichea2711 28-05-2021 12 1   Download

Gaining biological insights into molecular responses to treatments or diseases from omics data can be accomplished by gene set or pathway enrichment methods. A plethora of diferent tools and algorithms have been developed so far. Among those, the gene set enrichment analysis (GSEA) proved to control both type I and II errors well.

13p viwyoming2711 16-12-2020 16 1   Download

Distance based unsupervised clustering of gene expression data is commonly used to identify heterogeneity in biologic samples. However, high noise levels in gene expression data and relatively high correlation between genes are often encountered, so traditional distances such as Euclidean distance may not be effective at discriminating the biological differences between samples.

17p viflorida2711 30-10-2020 11 2   Download

The spatial distribution and colocalization of functionally related metabolites is analysed in order to investigate the spatial (and functional) aspects of molecular networks. We propose to consider community detection for the analysis of m/z-images to group molecules with correlative spatial distribution into communities so they hint at functional networks or pathway activity.

12p vijisoo2711 27-10-2020 9 0   Download

Notch signalling regulates cell fate in most tissues, promoting precursor cell proliferation in some, but differentiation in others. Accordingly, downregulation or overactivity variously contributes to cancer development. So far, little is known about Notch pathway activity and function in the normal urothelium and in urothelial carcinoma (UC).

13p vilisa271 22-09-2020 21 1   Download

Esophageal cancer (EC) is one of the most common cancers worldwide. The cancer-related inflammation pathway- signal transducer and activator of transition 3 (STAT3) signaling pathway has been reported to play critical role in its initiation and progression, while the way mediated its hyperactivation remains elusive so far.

11p vialabama2711 21-09-2020 9 0   Download

Neuroblastoma is the most common extracranial solid malignancy in childhood, responsible for 15% of all pediatric cancer deaths. It is an heterogeneous disease that does not always respond to classical therapy; so the identification of new and specific molecular targets to improve existing therapy is needed.

12p vidhaka2711 31-07-2020 13 2   Download

MLKL is the most important executor of necroptosis pathway. Recent studies have demonstrated that MLKL could serve as a potential prognostic biomarker for cancer patients. However, most studies reported so far are limited in discrete outcome and sample size.

10p vimanila2711 29-06-2020 17 0   Download

Salinity is one of the most aggressive environmental stresses that hamper crop productivity worldwide. Increased salt concentration in soil reduces plants ability to take up water. It also reduces nutrients availability, uptake and transport, and there distribution resulting nutritional imbalance in plant. The Salt Overly Sensitive (SOS) signalling pathway is crucial to mediate cellular signalling and to maintain ion homeostasis under salinity stress. Many HKT family plasma membrane transporters play an essential role in salt tolerance mechanism by regulating Na+ and K+ transportation.

6p nguaconbaynhay6 23-06-2020 12 0   Download

Chickpea seeds of two varieties magnetoprimed with 100 mT 1h static magnetic field were subjected to salinity stress (80 mM NaCl) from germination to maturity. Physiological traits such as total root length, surface area, volume of the roots, plant height, leaf area and dry weight were significantly improved in plants from magnetoprimed seeds of both the varieties. Total chlorophyll content enhanced significantly under priming in leaves of Pusa 1053 compared to Pusa 256 under all treatments.

13p trinhthamhodang3 12-02-2020 15 1   Download

Nội dung của bài giảng trình bày sự cần thiết, tổng quan về Clinical Pathway, hướng dẫn thực hiện quy trình điều trị, quy trình điều trị bệnh tiêu chảy cấp ở trẻ em; những lỗi thường gặp trong điều trị tiêu chảy cấp ở trẻ em; mục tiêu và chỉ số đánh giá quy trình điều trị tiêu chảy cấp; nội dung quy trình điều trị tiêu chảy cấp trẻ em, biểu mẫu; các biến đổi chấp nhận được.

7p cothumenhmong2 01-02-2020 46 2   Download