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Study the enzyme
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This study aims to investigate the role and mechanism of tubiquitin-conjugating enzyme E2 C (UBE2C) in acute myeloid leukemia (AML). Initially, UBE2C expression in leukemia was analyzed using the Cancer Genome Atlas database. Further, we silenced UBE2C expression using small-hairpin RNA (sh-RNA).
11p
vishanshan
27-06-2024
1
1
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Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the role of USP14 in the regulation of HCC development and progression remains unclear.
15p
vikoch
27-06-2024
1
1
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This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.
15p
vikoch
27-06-2024
1
1
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The study on essential oils of various plantparts and their biological activities continues to be an important area of research and developmen. In the continuation of our current research on the identification of bioactive substances from plants of North East India.
21p
viamancio
04-06-2024
2
0
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In this study, in order to valorize black-purple rice, we used commercial enzyme preparations to hydrolyze the raw starch from this material to produce an anthocyanin–containing glucose solution.
11p
viamancio
04-06-2024
3
0
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Currently, L-asparaginase isolated from terrestrial microorganisms has been employed for anticancer industrial production. This enzyme has the function of inhibiting the growth of acute lymphoblastic leukemia, Hodgkin's lymphomas and other cancers. In this study, for the first time, L-asparaginase (ASNase) productive capacity of forty marine bacteria originating from Khanh Hoa sea of Viet Nam was screened and reported.
13p
viamancio
04-06-2024
2
0
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Ebook "Plant lipid signaling protocols" is dedicated to the various experimental approaches by which plant signaling lipids can be studied. Experts in the field have contributed their knowledge and extensive experience to provide a collection of 27 chapters on the analysis of plant signaling lipids, including detailed protocols to detect various relevant compounds by targeted or nontargeted approaches.
319p
dongmelo
27-05-2024
3
2
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This study deals with the use of cellulase to hydrolyze glucoside isoflavones into aglycone forms. Choosing the appropriate enzyme and regimen will help improve the hydrolysis efficiency of isoflavone glucosides.
5p
vijaychest
16-05-2024
1
0
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This study has demonstrated the presence of two compounds Genipin and Geniposide in Gardenia jasminoides Ellis.) collected in Thanh Luong commune, Thanh Chuong district, Nghe An province using the 1 H-NMR and 13C-NMR.
5p
vijaychest
16-05-2024
1
1
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The study was carried out to investigate lipid and protein oxidation of herring (Sardinella gibbosa) that was treated with (2.5% w/v) sodium acetate at 4o C. After 3, 6, 9, and 12 days, lipid and protein oxidation were evaluated by indications such as pH value, peroxide (PV), thiobarbituric acid-reactive substances (TBARS), protease enzyme activity and sulfhydryl.
9p
dianmotminh02
03-05-2024
2
1
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In our study, the mixture of cellulase and pectinase were used to exploit plant matrix. The combination of these enzymes increased the extraction efficiency compared to single enzyme treatment. The fresh tea leaves, byproduct of the green tea processing, were utilized as materials for extracting. And the enzyme-assisted extraction was investigated. Firstly, the materials were treated with the mixture of cellulase and pectinase.
12p
dianmotminh02
03-05-2024
1
1
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In silico screening of alkaloids as potential inhibitors of HER2 protein for breast cancer treatment
his study focused on finding alkaloid compounds collected from Chemfaces database that inhibit HER2 enzyme employing computational methods such as molecular docking and ADMET prediction. Out of 118 phytochemicals docked to the ATP binding site of the HER2 kinase domain, 10 alkaloid compounds exhibited higher binding affinity than the reference inhibitor and satisfied the Lipinski’s rule of five. All compounds have good pharmacokinetic properties.
10p
dianmotminh02
03-05-2024
4
3
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Ebook "CtBP family proteins" are unique in several aspects. They were the first among proteins containing a metabolic enzyme fold to be implicated in transcriptional regulation. The vertebrate CtBPs exhibit distinct nuclear and cytosolic activities. The crystal struaures of CtBPl and molecular modeling studies have illuminated the molecular basis of its dual activity and the interaction with target peptides.
131p
ladongphongthanh1008
22-04-2024
5
2
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Ebook "Transgenesis and secondary metabolism" provides comprehensive reference information on the efficient production of secondary metabolites from plants by transgenesis and other genetic manipulation strategies. It reviews and summarizes selected important case studies in genetic methods applied to enhance the production of a given metabolite or a group of related or derived compounds.
652p
tracanhphuonghoa1007
22-04-2024
7
3
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The synthesized compounds' enzyme inhibition potential was tested against a-glucosidase, AChE, and BChE enzymes. As illustrated from the results of IC50, these compounds are observed as the active inhibitory potential for these enzymes. The cytotoxic activity by hemolytic Assay revealed that these compounds have mild exposure to cytotoxicity on RBCs.
10p
visergey
02-04-2024
0
0
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There are many evidences showing the fact that some hard conditions from environment, namely abiotic stress, could make several significantly negative impacts on crop production. However, some plant species can overcome these bad situations by complicated mechanisms. This study has shown the result of the construction the recombinant vector carrying CodA gene which could encode an enzyme, named choline oxidase, and is controlled by Rd29A promoter.
8p
vilarry
01-04-2024
5
1
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Synthesis of silver nanoparticles (AgNPs) using plant extracts extracted from Ganoderma lucidum in the buffer zone of Bach Ma National Park, Vietnam is a simple, convenient, economical, and environmentally friendly method. This study describes the biosynthesis of silver nanoparticles in both cases with and without ultrasonic assistance using Ganoderma lucidum extract as a reducing and protective agent.
9p
viritesh
02-04-2024
2
1
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Whether elevated blood pressure (BP) is a modifiable risk factor for atrial fibrillation (AF) is not established. We tested (1) whether the association between BP and risk of AF is causal, (2) whether it varies according to individual’s genetic susceptibility for AF, and (3) the extent to which specific BP-lowering drugs are expected to reduce this risk.
10p
vibransone
28-03-2024
3
2
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Ebook "Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes" has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides.
253p
tudohanhtau1006
29-03-2024
4
1
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Ebook "Nanobioelectrochemistry: From implantable biosensors to green power generation" describes some of the different electrochemical techniques that can be used to study new strategies for patterning electrode surfaces with enzymes, organelles, cells and biomimetic systems. Also, it focuses on how enzymes and microorganisms can be used as biological catalysts in fuel cells for green power generation.
144p
coduathanh1122
27-03-2024
2
1
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