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Survival and pathogenesis

Xem 1-19 trên 19 kết quả Survival and pathogenesis
  • Many mycobacterial species, including M. tuberculosis, grow extremely slowly in the laboratory and require 3–8 weeks of incubation on solid medium or at least 2 weeks in a radiometric liquid culture system (BACTEC). This slow growth often leads to delay in TB diagnosis. Nucleic acid amplification (NAA) methods allow for detection of mycobacterial DNA or RNA directly from the specimens before the culture results are available. The Food and Drug Administration (FDA) has approved two NAA tests for direct detection of M. tuberculosis from clinical specimens.

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  • Only 32% infants are exclusively breastfed during the first six months. This is an increase from 13% in 2003. Data from the 2003 and 2008 Kenya Demographic and Health Survey, show that although breastfeeding is a common practice in Kenya, mixed feeding rather than exclusive breastfeeding is practiced. There was a marked decline in exclusive breastfeeding rates between 1993/98 (17%) and 2003 (13%). Some of the contributing factors were confusing messages about breastfeeding in context HIV and AIDS.

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  • Schistosomiasis is not known to be associated with any malignant disease other than bladder cancer. Bladder cancer is still the most common malignant tumor among males in Egypt and some African and Middle East countries. However, the frequency rate of bladder cancer has declined significantly during the last 25 years. This drop is mainly related to the control of Schistosomiasis. Many studies have elucidated the pathogenic events of Schistosomal-related bladder cancer with a suggested theory of pathogenesis.

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  • But the Commission's hope for the future is conditional on decisive political action now to begin managing environmental resources to ensure both sustainable human progress and human survival. We are not forecasting a future; we are serving a notice - an urgent notice based on the latest and best scientific evidence - that the time has come to take the decisions needed to secure the resources to sustain this and coming generations. We do not offer a detailed blueprint for action, but instead a pathway by which the peoples of the world may enlarge their spheres of cooperation....

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  • The third reason stems from a different set of empirical findings. Barring sub-Saharan Africa over the past thirty years or so, gross income per head has grown in nearly all poor regions since the end of the Second World War. In addition, growth in world food production since 1960 has exceeded the world’s population growth: by an annual rate of 0.6 percent, approximately.This has been accompanied by improvements in a number of indicators of human welfare, such as the infant survival rate, life expectancy at birth, and literacy.

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  • Decreases in pH and ANC are often paral- leled by changes in element concentrations including increases in Al +3 concentrations and decreases in Ca +2 . High dissolved Al +3 concen- trations can have toxic effects on many types of aquatic biota, and at extreme levels few aquatic species can survive (Table 1). Organic forms of Al +3 are much less toxic than inorganic forms. Emerging research suggests that Ca +2 concentra- tions in streamwater are also an important bio- logical indicator.

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  • It is clear from above that the coverage levels of key interventions remain sub-optimal12 and require increased efforts to secure improved survival chances for children in their early stages of life. This will also contribute to improving maternal health and reduce maternal mortality. The level of contraceptive use has been low and terminal methods of sterilisation, which are not very effective in spacing between the deliveries, had the major share among the different methods used.

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  • Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the most common malignant myeloid disorder in adults. Several gene mutations such as in NPM1 (nucleophosmin 1) are involved in the pathogenesis and progression of AML. The aim of this study was to identify genes whose expression is associated with driver mutations and survival outcome. Genotype data (somatic mutations) and gene expression data including RNA-seq, microarray, and qPCR data were used for the analysis. Multiple datasets were utilized as training sets (GSE6891, TCGA, and GSE1159).

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  • PRKAA1 encodes α-subunit of 5-AMP-activated protein kinase (AMPK), which has been implicated in the pathogenesis of carcinoma of the stomach. Previous works have suggested that polymorphisms in the PRKAA1 may be associated with the risk of non-cardiac gastric cancer (NCGC).

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  • Uterine serous carcinoma (USC) is a rare but aggressive subtype of endometrial carcinoma. Largescale comprehensive efforts have resulted in an improved molecular understanding of its pathogenesis, and the p53 pathway has been proposed as a key player and is potentially targetable.

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  • Risk classification and prediction of prognosis in GIST is still a matter of debate. Data on the impact of age and gender as potential confounding factors are limited. Therefore we comprehensively investigated age and gender as independent risk factors for GIST

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  • An Entrepreneurship and Small Business BBS from Massey will provide a thorough understanding of this innovative business sector and equip you with the skills to be a part of it. Small business operators and entrepreneurs play key roles in our society. To survive they must constantly ask questions like, “Do I extend my operations?”, “Do I sell out?”, “How do I build on past success?”, “How do I balance home life with my work?”, and “How do I raise money to finance expansion?”. Massey University has been helping students answer these questions for more than 25 years.

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  • The intuition underpinning these results is as follows. In a highly connected system, the counterparty losses of a failing institution can be more widely dispersed to, and absorbed by, other entities. So increased connectivity and risk sharing may lower the probability of contagious default. But, conditional on the failure of one institution triggering contagious defaults, a high number of nancial linkages also increases the potential for contagion to spread more widely.

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  • Appropriate feeding practices are of fundamental importance for the survival, growth, development, health and nutrition of infants and children. The 1990’s saw an upsurge of several worldwide efforts to achieve this goal. Examples of this are the Innocenti Declaration on Breastfeeding (1990), the World Summit for Children (1990), The Earth Summit (1992) the International Conference on Nutrition (1992) and the International Conference on Population and Development (1994). All agreed on the need to create the right environment for women to breastfeed their children....

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  • Very limited evidence was available to inform the following recommendations on screening. No prospective studies have evaluated the impact of screening on survival, quality of life, or morbidity from treatment for skin cancer nor are there data on the adverse effects of screening for skin cancer. As experts in the treatment and epidemiology of skin cancer, the guideline panel members were aware that some individuals are at increased risk for skin cancer because of personal characteristics or history.

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  • Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Parkin in breast cancer remains largely unknown.

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  • Her2/neu is an oncogene that plays an important role in the pathogenesis of many cancer types. In bladder carcinoma (BC), the clinical significance of Her2/neu status remains under-investigated and poorly linked to the patients’ clinic-pathological features and survival status.

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  • Cholangiocarcinoma is characterized by late diagnosis and a poor survival rate. MicroRNAs have been involved in the pathogenesis of different cancer types, including cholangiocarcinoma. Our aim was to identify novel microRNAs regulating cholangiocarcinoma cell growth in vitro and in vivo.

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  • Construct a table to compare and contrast invasive ductal carcinoma (NOS), invasive lobular carcinoma, medullary carcinoma, colloid (mucinous) carcinoma, tubular carcinoma, and metaplastic carcinoma of the breast in terms of incidence, age predilection, etiology, pathogenesis, clinical presentation, gross and microscopic morphology, grade, molecular classification, patterns of spread, clinical course, prognostic indicators, treatment options, and survival rates, and indicate which are more common in males versus females.

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