Synthesis of new organic compounds

Objectives of the dissertation: Structured design of coxib - combretastatin hybrid compounds. Synthesize coxib - combretastatin hybrid compounds. Screening for anti-cancer and anti-inflammatory activities of hybrid compounds. Identifying anti-inflammatory and anti-cancer mechanisms of hybrid compounds. Docking of a hybrid coxib - combretastatin compound with two purpose effect COX2 and tubulin.

27p extraenglish 24-05-2021 8 3   Download

Goals of the study: Synthesis of new organic compounds (target) containing imidazole-5-one heterocycle; thiazolidine-2,4-dione heterocycle or 1,3,4-oxadiazoline heterocycle with different substituents in experimental conditions of Vietnam. Study on the properties, structures and biological activities of these compounds to contribute to the studies of both theory and application of heterocyclic compounds.

27p prisonbreak123 21-05-2021 25 4   Download

Objectives of the dissertation: Structured design of coxib - combretastatin hybrid compounds; synthesize coxib - combretastatin hybrid compounds; screening for anti-cancer and anti-inflammatory activities of hybrid compounds; icreening for anti-cancer and anti-inflammatory activities of hybrid compounds.

27p capheviahe27 23-02-2021 14 3   Download

The objectives of the thesis: Molecular docking studies on acetylcholinesterase were performed to predict the chalcone structure has good in silico AChE acetylcholinesterase inhibitory activity. The potential chalcone compounds were synthesized and studied for their in vitro and in vivo AChE inhibitory activities

25p xacxuoc4321 09-07-2019 40 7   Download