Systemic health diseases

Asthma, a pervasive chronic inflammatory ailment of the respiratory system, remains a global health conundrum. The Global Burden of Disease Study (GBD) of 2019 underscores its widespread impact, revealing that asthma afflicts 262 million individuals worldwide, translating into an age-standardized prevalence of 3,416 per 100,000 population.

11p vinara 11-01-2025 1 1   Download

Bacterial infections have a substantial impact on global health and can become serious if misdiagnosed with several diseases related to the central nervous, cardiovascular, and respiratory systems. The prognosis in patients with infectious disease strongly depends on early diagnosis and appropriate antibiotic therapy. We aimed to compare the accuracy of genus and species-level identification bacteria using biochemical testing and 16S rRNA sequence analysis.

8p viharuno 03-01-2025 3 2   Download

Hypertension is one of the major causes of cardiovascular diseases in the world. Periodontal disease is a chronic inflammatory disorder of the tissues surrounding the teeth. The objectives of this study were to determine the association between hypertension and periodontal parameters in periodontitis patients.

6p viuchiha 03-01-2025 4 2   Download

The core list presents a list of minimum medicine needs for a basic health‐care system, listing the most efficacious, safe and cost‐effective medicines for priority conditions. Priority conditions are selected on the basis of current and estimated future public health relevance, and potential for safe and cost‐effective treatment. The complementary list presents essential medicines for priority diseases, for which specialized diagnostic or monitoring facilities, and/or specialist medical care, and/or specialist training are needed.

45p kikyou751998 23-05-2012 447 38   Download

Endothelial cells are indispensable components of the vascular system, and play pivotal roles during development and in health and disease. Their properties have been studied extensively byin vivo analysis of genetically modified mice.

11p media19 06-03-2013 56 3   Download

Angiotensin-converting enzyme (ACE) and its homologue angiotensin-converting enzyme 2 (ACE2) are critical counter-regulatory enzymes of the renin–angiotensin system, and have been implicated in cardiac function, renal disease, diabetes, atherosclerosis and acute lung injury.

10p vinaphone15 28-02-2013 39 3   Download

Heterozygous loss-of-function mutations at the glucosecerebrosidase locus have recently been shown to be a potent risk factor for Lewy body disease. Based on this observation, we have re-evaluated the likelihood that the dif-ferent PARK loci (defined using clinical criteria for disease) may be misleading attempts to find common pathways to pathogenesis.

7p vinaphone15 28-02-2013 52 3   Download

The mammalian natriuretic peptide system, consisting of at least three ligands and three receptors, plays critical roles in health and disease. Exam-ination of genetically engineered animal models has suggested the signifi-cance of the natriuretic peptide system in cardiovascular, renal and skeletal homeostasis.

12p cosis54 05-01-2013 49 4   Download

The TEC family is ancient and constitutes the second largest family of cyto-plasmic tyrosine kinases. In 1993, loss-of-function mutations in theBTK gene were reported as the cause of X-linked agammaglobulinemia. Of all the existing 90 tyrosine kinases in humans, Bruton’s tyrosine kinase (BTK) is the kinase for which most mutations have been identified.

10p cosis54 05-01-2013 39 4   Download

Pesticides are used to protect crops from insects, weeds and diseases both in dryland and irrigated crop production in Viet Nam. However, reliance on pesticides in crop production system has the potential to cause environmental problems due to contamination of waterways and of produce, adversely affecting the Vietnamese environment and human health.

17p tam_xuan 02-03-2012 61 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An analysis of Liberia’s 2007 national health policy: lessons for health systems strengthening and chronic disease care in poor, post-conflict countries

14p panasonic03 16-12-2011 50 3   Download

Anne Sales*1, Christian Helfrich2, P Michael Ho3,4, Ashley Hedeen2, Mary E Plomondon3,4, Yu-Fang Li2, Alison Connors1 and John S Rumsfeld3,4 Address: 1University of Alberta, Edmonton, Alberta, Canada, 2VA Puget Sound Health Care System, Seattle, Washington, USA, 3VA Eastern Colorado Health Care System, Denver, Colorado, USA and 4University of Denver Health Sciences Center, Denver, Colorado, USA Email: Anne Sales* - anne.sales@ualberta.ca; Christian Helfrich - christian.helfrich@va.gov; P Michael Ho - michael.ho@va.gov; Ashley Hedeen - ashley.hedeen@va.gov; Mary E Plomondon - meg.

12p toshiba23 11-12-2011 65 3   Download

Abstract Although gait change is considered a useful indicator of severity in animal models of Parkinson's disease, systematic and extensive gait analysis in animal models of neurological deficits is not well established. The CatWalk-assisted automated gait analysis system provides a comprehensive way to assess a number of dynamic and static gait parameters simultaneously. In this study, we used the Catwalk system to investigate changes in gait parameters in adult rats with unilateral 6-OHDA-induced lesions and the...

10p toshiba23 18-11-2011 54 7   Download

Abstract Glucose homeostasis in humans is an important factor for the functioning of nervous system. Hypoglycemia and hyperglycemia is found to be associated with central and peripheral nerve system dysfunction. Changes in acetylcholine receptors have been implicated in the pathophysiology of many major diseases of the central nervous system (CNS). In the present study we showed the effects of insulin induced hypoglycemia and streptozotocin induced diabetes on the cerebellar cholinergic receptors, GLUT3 and muscle cholinergic activity. Results showed enhanced binding parameters and gene...

9p toshiba23 18-11-2011 55 2   Download

Caffeine, a nonselective adenosine A1 and A2A receptor antagonist, is the most widely used psychoactive substance in the world. Evidence demonstrates that caffeine and selective adenosine A2A antagonists interact with the neuronal systems involved in drug reinforcement, locomotor sensitization, and therapeutic effect in Parkinson's disease (PD). Evidence also indicates that low doses of caffeine and a selective adenosine A2A antagonist SCH58261 elicit locomotor stimulation whereas high doses of these drugs exert locomotor...

10p toshiba23 18-11-2011 51 2   Download

Genome Institute of Singapore, Agency for Science, Technology and Research, 60 Biopolis Street, Singapore, 138672. †National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. ‡Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892-4264, USA. Correspondence: Sheue-yann Cheng. E-mail: sycheng@helix.nih.gov

0p thulanh21 15-11-2011 49 2   Download