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Therapy assessment
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Accurate assessment of axillary status after neoadjuvant therapy for breast cancer patients with axil‑ lary lymph node metastasis is important for the selection of appropriate subsequent axillary treatment decisions. Our objectives were to accurately predict whether the breast cancer patients with axillary lymph node metastases could achieve axillary pathological complete response (pCR).
13p
vishanshan
27-06-2024
2
1
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The objective of this study was to describe real-world adjuvant therapy (AT) use by disease substage and assess determinants of treatment choice among patients with stage III melanoma. This non-interventional retrospective study included survey responses and data from patient records pro‑ vided by US medical oncologists.
13p
vishanshan
27-06-2024
2
1
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The present research was designated to investigate the potential of ZnONP nanocomposites as a cancer chemotherapeutic-based drug delivery system and to assess the anti-tumor and anti-inflammatory effectiveness of ZnONP nanocomposites combination with systemic chemotherapeutic drugs doxorubicin (DOX) and folic acid (FA) in Ehrlich ascites carcinoma (EAC) tumor cell line both in vitro and in vivo.
16p
vishanshan
27-06-2024
2
1
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A new class of antibody-based drug therapy with the potential for disease modification is now available for Alzheimer’s disease (AD). However, the complexity of drug eligibility, administration, cost, and safety of such disease modifying therapies (DMTs) necessitates adopting new treatment and care pathways.
12p
vishanshan
27-06-2024
2
1
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Breast cancer (BrCa) is a predominant malignancy, with metastasis occurring in one in eight patients, nearly half of which target the bone, leading to serious complications such as pain, fractures, and compromised mobility. This study aims to assess the efficacy of CTRA in monitoring osteolytic lesions’ progression and response to therapy, suggesting its potential superiority over existing methodologies in guiding treatment strategies.
13p
vishanshan
27-06-2024
1
1
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To explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the efficacy of targeted therapy. Methods A retrospective analysis was conducted on the NGS test of 357 cases of advanced lung adenocarcinoma LBC specimens and compared with results of histological specimens to assess the consistency. The impact of tumor cellularity on NGS test results was evaluated.
8p
vikoch
27-06-2024
1
1
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In the era of targeted therapies, the influence of aging on cancer management varies from one patient to another. Assessing individual frailty using geriatric tools has its limitations, and is not appropriate for all patients especially the youngest one.
8p
vikoch
27-06-2024
1
1
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This study aimed to identify metabolic subtypes in ESCA, explore their relationship with immune land‑ scapes, and establish a metabolic index for accurate prognosis assessment. Methods Clinical, SNP, and RNA-seq data were collected from 80 ESCA patients from the TCGA database and RNAseq data from the GSE19417 dataset. Metabolic genes associated with overall survival (OS) and progression-free survival (PFS) were selected, and k-means clustering was performed.
16p
vikoch
27-06-2024
1
1
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There are an estimated 55 million Americans over the age of 50 who have low bone mass. This easy-to-understand guide helps readers assess their risk and find a practical approach to the diagnosis, treatment, and prevention of osteoporosis. It covers bone density tests and a wide range of treatment options for osteoporosis-from hormone replacement therapy and acupuncture to calcium-rich foods, supplements, and exercise-and offers pointers on preventing broken hips and other common fractures.
314p
zizaybay1104
29-05-2024
3
2
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Part 1 book "Clinical surgery in general" includes content: Resuscitation, trauma, clinical diagnosis, investigations, imaging techniques, influence of coexisting disease, immunity in surgery, haematological assessment and blood component therapy, nutritional support, clinical pharmacology, evidence-based practice, decision making, consent for surgical treatment, preoperative preparation for surgery, preoperative assessment and anaesthesia.
213p
zizaybay1101
30-04-2024
11
2
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Speech therapy uses a combination of approaches to assess speech and language, including analysis of spontaneous speech, use of standardized scales and assessment by the child’s parents and/or preschool teachers. In this paper, we present the Teddy Talk Test. Using a sample of sixteen children aged 4 to 5 years, we examined whether the test provided representative data on child language development.
11p
viarnault
25-04-2024
3
1
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Tumor mutational burden (TMB; the quantity of aberrant nucleotide sequences a given tumor may harbor) has been associated with response to immune checkpoint inhibitor therapy and is gaining broad acceptance as a result. However, TMB harbors intrinsic variability across cancer types, and its assessment and interpretation are poorly standardized.
16p
vibransone
28-03-2024
2
2
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The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inability to study complex signaling networks in patient tumors.
19p
vioraclene
31-03-2024
3
2
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Part 1 book "Medical-Surgical nursing" includes contents: Principles of nursing assessment; principles of drug administration; principles of intravenous therapy; principles of nutritional care; principles of infection prevention and control; principles of acute care for older people; principles of end of life care; principles of perioperative nursing; principles of high dependency nursing, principles of emergency nursing.
177p
muasambanhan09
16-03-2024
0
0
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Part 1 book "Medical surgical nursing - Assessment and management of clinical problems" includes content: Professional nursing practice; health disparities and culturally competent care; health history and physical examination; patient and caregiver teaching; chronic illness and older adults; complementary and alternative therapies; stress and stress management; sleep and sleep disorders; pain,... and other contents.
222p
muasambanhan08
01-03-2024
1
0
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Part 1 book "BSAVA manual of canine and feline - Rehabilitation, supportive and palliative care - Case studies in patient management" includes content: Introduction; acute pain - Assessment and management; chronic pain, fear, anxiety and conflict in companion animals; principles ot clinical nutrition, obesity and weight management, immune-modulating dietary components and nutraceuticals, an introduction to physical therapies, physiotherapy and physical rehabilitation,... and other contents.
176p
muasambanhan08
04-03-2024
3
0
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Pathogenic germline variants (PGVs) in certain genes are linked to higher lifetime risk of developing breast cancer and can influence preventive surgery decisions and therapy choices. Public health programs ofer genetic screening based on criteria designed to assess personal risk and identify individuals more likely to carry PGVs, dividing patients into screened and non-screened groups.
20p
vicwell
29-02-2024
7
1
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Part 1 book "Handbook of pediatric dentistry" includes content: Child assessment, child management, dental caries, fluoride modalities, restorative paediatric dentistry, pulp therapy for primary and immature permanent teeth, trauma management.
191p
muasambanhan08
23-02-2024
5
1
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Part 1 book "The veterinary nurse's practical guide to small animal anaesthesia" includes content: Pre-anaesthetic assessment and premedication, interpreting blood results, cardiovascular physiology, respiratory physiology and ventilation, blood pressure regulation and monitoring, capnography and spirometry, pulse oximetry, practical ecgs, fluid therapy
178p
muasambanhan07
20-02-2024
4
0
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Part 1 book "Small animal emergency and critical care for veterinary technicians" includes content: Critical thinking -skill of observation and interpretation; monitoring of the critically ill or injured patient; patient’s lifeline - intravenous catheter, fluid therapy, transfusion medicine, nutritional support for the critically ill patient, oxygen therapy techniques, mechanical ventilation, pain assessment and treatment, supporting the critically ill or injured through physical rehabilitation techniques,... and other contents.
450p
muasambanhan05
22-01-2024
8
2
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