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Transfused children
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Postoperative bleeding is a major problem in children undergoing complex pediatric cardiac surgery. The primary aim of this prospective observational study was to evaluate the effect of an institutional approach consisting of early preventive fibrinogen, prothrombin complex and platelets administration on coagulation parameters and postoperative bleeding in children. The secondary aim was to study the rate of re-intervention and postoperative transfusion, the occurrence of thrombosis, length of mechanical ventilation, ICU stay and mortality.
9p
vidietmarhopp
29-12-2021
11
0
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Patient blood management programs should be applied to the pediatric population, but little is known about the current transfusion practice of pediatric burn injury patients. This retrospective study was performed to evaluate the practice of red blood cell (RBC) transfusion in children with burn injury, their predictive factors, and adherence to the German transfusion guideline.
8p
vidietmarhopp
28-12-2021
14
0
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Sri Lanka has a high prevalence of β-thalassaemia major. Clinical management is complex and long term and includes regular blood transfusion and iron chelation therapy. The economic burden of β-thalassaemia for the Sri Lankan healthcare system and households is currently unknown.
7p
viorochimaru2711
29-05-2020
12
1
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In resource-poor settings, transfused children often experience recurrence of severe anemia (SA) following discharge from hospital. This study determined the factors associated with recurrent severe anemia (RSA) among previously transfused Ugandan children aged less than 5 years.
7p
vidublin2711
13-01-2020
10
1
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Children with Sickle Cell Disease (SCD) show endocrine complications and metabolic alterations. The physiopathology of these conditions is not completely understood: iron overload due to chronic transfusions, ischemic damage, and inflammatory state related to vaso-occlusive crises may be involved.
9p
vidublin2711
13-01-2020
14
0
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Twin-to-twin transfusion syndrome (TTTS) is a serious complication of 10–15% of twin or triplet pregnancies in which multiple fetuses share a single placenta. Communicating placental vessels allow one fetus (the donor) to pump blood to the other (the recipient).
11p
vidublin2711
13-01-2020
13
1
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Accelerated oxidative damage is one of the hallmarks in both sickle cell disease (SCD) and thalassemia major (TM). A decreased antioxidant level is found in both diseases. Our study was carried out to evaluate the variation in serum levels of Selenium and Vitamin E among a group of transfusion dependant Egyptian SCD and TM patients, further more to correlate these levels with iron overload status or transfusion requirements.
7p
trinhthamhodang1
16-11-2019
41
2
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One study assessed the impact of hydroxyurea on secondary stroke prevention by enrolling 35 children who needed to discontinue their chronic transfusion protocol. The average hydroxyurea dose was 27 mg/kg/day, and the children were treated for a mean of 42 months. The rate of recurrent ischemic events was 5.7 per 100 patient-years, which is better than was seen in another study in which children discontinued transfusions without starting hydroxyurea.
85p
can_thai
12-12-2012
56
3
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Hematopoietic Stem Cell Transplantation This is the best therapy for the young patient with a fully histocompatible sibling donor (Chap. 108). Human leukocyte antigen (HLA) typing should be ordered as soon as the diagnosis of aplastic anemia is established in a child or younger adult. In transplant candidates, transfusion of blood from family members should be avoided so as to prevent sensitization to histocompatibility antigens; while transfusions in general should be minimized, limited numbers of blood products probably do not seriously affect outcome.
5p
thanhongan
07-12-2010
64
4
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