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Tumors including lung
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Methylation of the promoters of SHOX2 and RASSF1A (LungMe®) exhibits promise as a potential molecular biomarker for diagnosing lung cancer. This study sought to assess the aberrant methylation of SHOX2 and RASSF1A in broncho-exfoliated cells (BEC) and compare it with conventional cytology, histology examination, immunohistochemistry, and serum tumor markers to evaluate the overall diagnostic efficiency for lung cancer.
14p
vikoch
27-06-2024
3
1
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The impact of immune checkpoint inhibitors (ICIs) based treatments on non-small cell lung cancers (NSCLCs) with RET fusions remains poorly understood. Methods We screened patients with RET fusions at the First Affiliated Hospital of Zhengzhou University and included those who were treated with ICIs based regimens for further analysis.
9p
vikoch
27-06-2024
2
1
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Part 2 book "Robbins basic pathology" includes content: Heart, hematopoietic and lymphoid systems, lung, kidney and its collecting system, oral cavities and gastrointestinal tract, liver and gallbladder; male genital system and lower urinary tract; female genital system and breast; bones, joints, and soft tissue tumors, peripheral nerves and muscles; central nervous system; skin.
505p
zizaybay1101
30-04-2024
2
2
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Part 2 book "Pocket companion to Robbins cotran pathologic basis of disease" includes content: Red blood cells andbleeding disorders; the lung; head and neck; the gastrointestinal tract; liver and biliary tract; the pancreas; the kidney; the lower urinary tract and male genital system; the female genital tract; the breast; the endocrine system; the skin; bones, joints, and soft tissue tumors; peripheral nerve and skeletal muscle; the central nervous system; the eye.
432p
muasambanhan10
06-04-2024
4
0
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Part 2 book "Small animal soft tissue surgery" includes content: Pectus excavatum; surgery of the thoracic wall; tumors of the thoracic wall; flail chest; pyothorax in dogs and cats oronasal and oroantral fistula; cleft lip and palate; brachycephalic airway syndrome; laryngeal paralysis; laryngeal neoplasia; tracheal surgery; surgical diseases of the lungs,... and other contents.
695p
muasambanhan07
20-02-2024
9
0
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The malignant behaviors of lung cancers are affected by not only cancer cells but also many kinds of stromal cells in tumor microenvironment (TME), including macrophages. Macrophages have been proven to extensively influence tumor progression through several mechanisms, among which switching of macrophages from proinflammatory phenotypes (M1-like) to anti-inflammatory phenotypes (M2-like) mediated by transcription factors such as nuclear factor κB (NF-κB) is the most crucial event. The regulation of NF-κB has been well studied, however some details remain fuzzy.
18p
vileonardodavinci
23-12-2023
3
2
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Ankyrin repeat domain 49 (ANKRD49) has been found to be highly expressed in multiple cancer including lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC). Considering the heterogeneity of tumor cells, the function and mechanism of ANKRD49 in NSCLC need more NSCLC-originated cells to clarify.
18p
vileonardodavinci
23-12-2023
4
2
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This study aimed to determine the effectiveness of liquid biopsy in detecting epidermal growth factor receptor (EGFR) mutations at diagnosis, disease progression, and intermediate stages. This prospective, multicenter, observational study included 30 patients with non-small cell lung cancer treated with afatinib, harboring a major EGFR mutation confirmed by tumor tissue biopsy
11p
vialfrednobel
23-12-2023
3
3
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According to the histopathological classification of lung tumors of the World Health Organization (WHO) 2015, update 2021, the adenocarcinoma group includes the following subtypes: (1) minimally invasive adenocarcinoma (MIA); (2) Invasive non-mucinous carcinoma (INMA); (3) Invasive mucinous carcinoma (IMA); (4) Colloidal adenocarcinoma (CA); (5) Fetal cancer (FA); (6) Enteric-type adenocarcinoma (EA).
8p
visoros
01-11-2023
1
1
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Tumor necrosis factor receptor-associated factor 3 (TRAF3) has specific regulatory effects on a wide range of diseases, including tumors. However, the effect and mechanism of TRAF3 on lung adenocarcinoma (LUAD) are still unknown. The aim of the present study was to make clear the role and potential mechanism of TRAF3 in LUAD.
9p
visharma
20-10-2023
5
2
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Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous cell carcinoma and gastric cancer. LRPPRC exerts its tumor-promoting effects mainly by regulating mitochondrial homeostasis and inducing oxidative stress.
11p
visharma
20-10-2023
4
2
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Targeting the immune checkpoint of programmed death ligand 1 (PDL1) and programmed cell death protein 1 (PD-1) with immunotherapy has improved the treatment of many tumors including non-small cell lung cancer (NSCLC). Checking PD-L1 status must be done during the course of therapy.
4p
viintuit
26-09-2023
0
0
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Extra-skeletal osteosarcoma (ESOS) is a rare neoplasm that represents less than 2% of all soft tissue sarcomas. Common reported sites of involvement include limbs, retroperitoneum, chest wall and buttocks. ESOS arising primarily in parenchymatous organs are extremely uncommon, with the involvement of the urinary bladder is even rarer. We herein report a case of primary ESOS of the urinary bladder in a 48 year-old male patient.
4p
viintuit
26-09-2023
3
0
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Part 2 book "Robbins and cotran review of pathology" includes content: The lung; head and neck; gastrointestinal tract; liver and biliary tract; pancreas; kidney; the lower urinary tract and male genital system; female genital tract; the breast; the endocrine system; the skin; bones, joints, and soft tissue tumors; peripheral nerve and skeletal muscle; central nervous system; the eye; final review and assessment.
268p
oursky03
21-08-2023
6
2
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Long noncoding RNAs contribute to various infammatory diseases, including sepsis. We explore the role of small nucleolar RNA host gene 16 (SNHG16) in sepsis-mediated acute lung injury (ALI) and infammation.
14p
vimackenziebezos
29-11-2021
7
3
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Paclitaxel (Taxol) is a microtubule-stabilizing drug used to treat several solid tumors, including ovarian, breast, non-small cell lung, and pancreatic cancers. The current treatment of ovarian cancer is chemotherapy using paclitaxel in combination with carboplatin as a frontline agent, and paclitaxel is also used in salvage treatment as a second line drug with a dose intensive regimen following recurrence.
13p
vimahuateng
26-11-2021
12
0
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Deleted in malignant brain tumors 1 (DMBT1) is an innate defence protein expressed in the lungs of preterm infants and adults. Recent studies showed that DMBT1 is important in angiogenesis and can bind to different growth factors including VEGF.
9p
vimontana2711
05-04-2021
13
3
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Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors all over the world. In recent years, long non-coding RNAs (lncRNAs) have been proven to participate in the development of different cancers, including NSCLC.
11p
vimichigan2711
26-03-2021
8
2
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Acute lung injury (ALI) is characterized by infammation and oxidative stress. Nuclear factor-kappaB (NF-κB) mediates the expression of various infammation-related genes, including the NADPH oxidase family. This study aimed to identify the potential regulatory role of NF-κB on NADPH oxidases in tumor necrosis factor-α (TNF-α)- induced oxidative stress in human alveolar epithelial cells.
12p
vimichigan2711
26-03-2021
10
1
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Insulinoma associated-1 (INSM1) gene is expressed exclusively in early embryonic neuroendocrine tissues, but has been found highly re-activated in most of the neuroendocrine tumors including small cell lung carcinoma.
10p
vimaine2711
26-03-2021
10
1
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