Type of family

The present study examined the relationships of a set of independent variables (Age, Education, Types of College, Experience, Pattern of Remuneration, Marital Status, Type of Family, Size of Family) with job satisfaction among Female Assistant Professors of private colleges.

12p guineverehuynh 22-06-2020 5 0   Download

The regulator of ubiquitous kinase (Ruk) protein, also known as CIN85 or SETA, is an adaptor-type protein belonging to the CD2AP/CMS family. It was found in complexes with many signaling proteins, including phos1 phoinositol (PtdIns) 3-kinase (EC 2.7.1.137), Cbl, GRB2, p130Cas and Crk. Functional analysis of these interactions, implicated Ruk in the regulation of apoptosis, receptor endocytosis and cytoskeletal rearrangements.

7p research12 01-06-2013 28 4   Download

Two genes (CM-AAT1 and CM-AAT2) with strong sequence homology (87% identity at the protein level) putatively involved in the formation of aroma volatile esters have been isolated from Charentais melon fruit. They belong to a large and highly divergent family of multifunctional plant acyl-transferases and show at most 21% identity to the only other fruit acyl-transferase characterized so far in strawberry. RT-PCR studies indicated that both genes were specifically expressed in fruit at increasing rates in the early and mid phases of ripening.

8p research12 01-06-2013 53 4   Download

The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. We have studied the implication of CD53 antigen in signal transduction by determining the effect of its ligation on the c-Jun N-terminal kinase (JNK) in different cell types. Ligation of the rat or human CD53 antigen induces a threeto fourfold transient activation of JNK activity that peaks at 3–5 min. The effect was detected by assaying the endogenous or exogenous (transfected) JNK activity....

10p research12 01-06-2013 45 6   Download

Double-stranded RNA-activated protein kinase (PKR), a serine/threonine kinase, is activated in virus-infected cells and acts as an antiviral machinery of type I interferons. PKR controls several stress response pathways induced by double-stranded RNA, tumor necrosis factor-aor lipo-polysaccharide, which result in the activation of stress-acti-vated protein kinase/c-Jun NH2 -terminal kinase and p38 of the mitogen-activated protein kinase family.

7p tumor12 22-04-2013 47 3   Download

Monoclonal nonspecific suppressor factor (MNSF) is a cytokine with antigen nonspecific suppressive activity. MNSFb(a subunit of MNSF) is a 14.5kDa fusion protein consisting of a proteinwith 36%identitywith ubiquitin and ribosomal protein S30. The ubiquitin-like segment (Ubi-L) may be cleaved from MNSFbin the cytosol. Recently, we have observed that Ubi-L covalently binds to intracellular proteins in mitogen-activated murine T-helper type 2 clone, D.10 cells.

7p tumor12 20-04-2013 34 3   Download

A100-kDa proteinwith endoglucanase activitywas purified from Triton X-100 extract of cells of the thermoacidophilic Gram-positive bacterium Alicyclobacillus acidocaldarius. The enzyme exhibited activity towards carboxy methyl cel-lulose and oat spelt xylan with pH and temperature optima of 4 and 80
C, respectively. Cloning and nucleotide sequence analysis of the corresponding gene (celB) revealed an ORF encoding a preprotein of 959 amino acids which is consistent with an extracellular localization.

10p tumor12 20-04-2013 34 2   Download

The a-amylase family (glycoside hydrolase family 13; GH 13) contains enzymes with approximately 30 specifi-cities. Six types of enzyme from the family can possess a C-terminal starch-binding domain (SBD): a-amylase, maltotetraohydrolase, maltopentaohydrolase, maltogenic a-amylase, acarviose transferase, and cyclodextrin glu-canotransferase (CGTase). Such enzymes are multidomain proteins and those that contain an SBD consist of four or five domains, the former enzymes being mainly hydrolases and the latter mainly transglycosidases. ...

11p tumor12 20-04-2013 33 2   Download

Sequence analysis of aPaenibacillussp. BP-23 recombinant clone coding for a previously described endoglucanase revealed the presence of an additional truncated ORF with homology to family 48 glycosyl hydrolases. The corres-ponding 3509-bp DNA fragment was isolated after gene walking and cloned inEscherichia coliXl1-Blue for expres-sion and purification. The encoded enzyme, a cellulase of 1091 amino acids with a deduced molecular mass of 118 kDa and a pI of 4.

7p fptmusic 16-04-2013 53 4   Download

Tumor necrosis factor-a converting enzyme (TACE or ADAM17) is a member of the ADAM (a disintegrin and metalloproteinase) family of type I membrane proteins and mediates the ectodomain shedding of various membrane-anchored signaling and adhesion proteins. TACE is syn-thesized as an inactive zymogen, which is subsequently proteolytically processed to the catalytically active form.We have identified the proprotein-convertases PC7 and furin to be involved in maturation of TACE.

8p fptmusic 16-04-2013 39 3   Download

Ferredoxin (flavodoxin)-NADP(H) reductases (FNR) are ubiquitous flavoenzymes that deliver NADPH or low potential one-electron donors (ferredoxin, flavodoxin) to redox-based metabolisms in plastids, mitochondria and bacteria. The plant-type reductase is also the basic prototype for one of the major families of flavin-containing electron transferases that display common functional and structural properties.

16p fptmusic 16-04-2013 41 2   Download

Type I antifreeze proteins (AFPs) are usually small, Ala-richa-helical poly-peptides found in right-eyed flounders and certain species of sculpin. These proteins are divided into two distinct subclasses, liver type and skin type, which are encoded by separate gene families. Blood plasma from Atlantic (Liparis atlanticus) and dusky (Liparis gibbus) snailfish contain type I AFPs that are significantly larger than all previously described type I AFPs.

10p fptmusic 12-04-2013 50 2   Download

Mucin type O-glycosylation is a widespread modification of eukaryotic pro-teins. The transfer of N-acetylgalactosamine to selected serine or threonine residues is catalyzed by a family of polypeptide N-acetylgalactosaminyl-transferases localized in the Golgi apparatus. The most abundant elonga-tion of O-glycans is the addition of a b1-3 linked galactose by the core-1 b1-3 galactosyltransferase (core-1b3GalT), thereby building the T-antigen or core-1 structure Gal(b1-3)GalNAc(a1-O).

11p fptmusic 11-04-2013 35 4   Download

The mammalian members of the inorganic phosphate (Pi ) transporter (PiT) family, the type III sodium-dependent phosphate (NaP i) transporters PiT1 and PiT2, have been assigned housekeeping Pi transport functions and are suggested to be involved in chondroblastic and osteoblastic mineralization and ectopic calcification.

15p fptmusic 11-04-2013 39 2   Download

Lectins belonging to the jacalin-related lectin family are distributed widely in the plant kingdom. Recently, two mannose-specific lectins having tan-dem repeat-type structures were discovered in Castanea crenata(angio-sperm) and Cycas revoluta(gymnosperm). The occurrence of such similar molecules in taxonomically less related plants suggests their importance in the plant body.

16p awards 06-04-2013 36 3   Download

The xylanase inhibitor protein I (XIP-I), recently identified in wheat, inhib-its xylanases belonging to glycoside hydrolase families 10 (GH10) and 11 (GH11). Sequence and structural similarities indicate that XIP-I is related to chitinases of family GH18, despite its lack of enzymatic activity. Here we report the identification and biochemical characterization of a XIP-type inhibitor from rice.

11p awards 06-04-2013 30 3   Download

Hu-K4 is a human protein homologous to the K4L protein of vaccinia virus. Due to the presence of two HKD motifs, Hu-K4 was assigned to the family of Phospholipase D proteins although so far no catalytic activity has been shown. The Hu-K4 mRNA is found in many human organs with highest expression levels in the central nervous system. We extended the ORF of Hu-K4 to the 5¢ direction. As a consequence the protein is 53 amino acids larger than originally predicted, now harbouring a putative transmembrane domain....

0p awards 06-04-2013 39 3   Download

Transglutaminases form a large family of intracellular and extracellular enzymes that catalyse the Ca 2+ -dependent post-translational modification of proteins. Despite significant advances in our understanding of the biolo-gical role of most mammalian transglutaminase isoforms, recent findings suggest new scenarios, most notably for the ubiquitous tissue transglutami-nase.

17p awards 05-04-2013 45 3   Download

In order to study the role of peroxisome proliferator-acti-vated receptor ain mouse intestine, its agonist-induced proteins were identified by peptide mass fingerprinting fol-lowed byNorthern blot analysis using their cDNAs. One of the most remarkably induced proteins was identified as 17b-hydroxysterol dehydrogenase type 11. Its very rapid induction by various agonists was most efficient in intestine and then in liver.

0p awards 05-04-2013 41 2   Download

The prolyl oligopeptidase (POP) family of serine proteases includes prolyl oligopeptidase, dipeptidyl peptidase IV, acylaminoacyl peptidaseandoligopeptidase B.The enzymes of this family specifically hydrolyze oligopeptides with less than 30 amino acids.Many of the POP family enzymes have evoked pharmaceutical interest as they have roles in the regulationof peptide hormones and are involved in a variety of diseases such as dementia, trypanosomiasis and type 2 diabetes.

11p dell39 03-04-2013 58 4   Download