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ADSCs and adipocytes are the main producers in the autotaxin– lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro
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Breast cancer is the most common malignancy in women affecting one out of eight females throughout their lives. Autotaxin (ATX) is upregulated in breast cancer which results in increased lysophosphatidic acid (LPA) formation within the tumor.
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