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Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

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A series of RNA-cleaving or DNA-cleaving DNAzymes have been obtained by in vitro selection. However, engineering an allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities is very challenging. We used an in vitro-selected pistol-like (PL) DNAzyme as a DNA scaffold for designing a DNAzyme with dual catalytic activities.

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Nội dung Text: Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities

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