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Báo cáo khoa học: Assessment of telomere length and factors that contribute to its stability

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:15

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Short strands of tandem hexameric repeats known as telomeres cap the ends of linear chromosomes.These repeats protect chromosomes from degradation and prevent chro-mosomal end-joining, a phenomenon that could occur due to the end-replicationproblem.Telomeres aremaintainedby the activity of the enzyme telomerase.The total number of telomeric repeats at the terminal end of a chromosome determines the telomere length, which in addition to its importance in chromosomal stabilization is a useful indica-tor of telomerase activity in normal and malignant tissues....

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