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Báo cáo khoa học: b3-Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

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White and brown adipocytes are usually located in distinct depots; however, in response to cold, brown adipocytes appear in white fat. This response is mediated by b-adrenoceptors but there is a controversy about the sub-type(s) involved. In the present study, we exposed to cold b3 -adrenoceptor knockout mice (b3KO) on a C57BL/6J geneticbackgroundandmeasured inwhiteadipose tissue the density of multilocular cells and the expression of the brown adipocyte marker uncoupling protein-1 (UCP1).

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Nội dung Text: Báo cáo khoa học: b3-Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat

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