Báo cáo khoa học: Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution
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The SUMO proteins are a class of small ubiquitin-like modifiers. SUMO is attached to a specific lysine side chain on the target protein via an isopeptide bond with its C-terminal glycine.Thereareat least fourSUMOproteins in humans, which are involved in protein trafficking and tar- geting. A truncated human SUMO-2 protein that contains residues 9–93 was expressed inEscherichia coliand crystal- lized in two different unit cells, with dimensions of a ¼b¼ 75.25 A ˚ ,c¼29.17 A ˚ and a¼b¼74.96 A ˚ ,c¼33.23 A ˚ , both belonging to the rhombohedral space groupR3. They diffractedX-rays to1.6 A˚ and1.2 A ˚ resolution, respectively....
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