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Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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The function of the epidermal growth factor receptor (EGFR) is dysregu-lated in various types of malignancy as a result of gene amplification, mutations, or abnormally increased ligand production. Therefore, the tyro-sine kinase activity of the EGFR is a promising therapeutic target.

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Nội dung Text: Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors

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