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Báo cáo khoa học: In vitro characterization of Synechocystis CYP120A1 revealed the first nonanimal retinoic acid hydroxylase
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Retinoids are C20 apocarotenoids that have various important functions in metazoans. In addition, several findings suggest their occurrence in eubac-teria, including cyanobacteria. It has been shown that the Synechocystis cytochrome P450 enzyme CYP120A1 is a retinoic acid-binding polypeptide. In this work, we determined the reaction catalyzed by CYP120A1 and investigated its substrate specificity in vitro.
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