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Báo cáo khoa học: Interaction between catalytically inactive calpain and calpastatin Evidence for its occurrence in stimulated cells

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:9

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Conformational changes in the calpain molecule following interaction with natural ligands can be monitored by the binding of a specific monoclonal antibody directed against the catalytic domain of the protease. None of these conformational states showed catalytic activity and probably repre-sent intermediate forms preceding the active enzyme state.

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Nội dung Text: Báo cáo khoa học: Interaction between catalytically inactive calpain and calpastatin Evidence for its occurrence in stimulated cells

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