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Báo cáo khoa học: Molecular structures and functional relationships in clostridial neurotoxins
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The seven serotypes ofClostridium botulinumneurotoxins (A–G) are the deadliest poison known to humans. They share significant sequence homo-logy and hence possess similar structure–function relationships. Botulinum neurotoxins (BoNT) act via a four-step mechanism, viz.,
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