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Báo cáo khoa học: Mutual effects of proton and sodium chloride on oxygenation of liganded human hemoglobin Oxygen affinities of the a and b subunits

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:11

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The different effects of pH and NaCl on individual O2-binding properties ofaandbsubunits within liganded tetramer and dimer of human hemo-globin (HbA) were examined in a number of laser time-resolved spectro-scopic measurements. A previously proposed approach [Dzhagarov BM & Lepeshkevich SV (2004)Chem Phys Lett390, 59–64] was used to determine the extent of subunit dissociation rate constant difference and subunit affinity difference from a single flash photolysis experiment.

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Nội dung Text: Báo cáo khoa học: Mutual effects of proton and sodium chloride on oxygenation of liganded human hemoglobin Oxygen affinities of the a and b subunits

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