Báo cáo khoa học: Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:9

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We report a comprehensive physicochemical characteriza-tion of a glycoglycerolipid from Mycoplasma fermentans, MfGl-II, in relation to its bioactivityand compared thiswith the respective behaviors of phosphatidylcholine (PC) and a bacterial glycolipid, lipopolysaccharide (LPS) from deep rough mutantSalmonella minnesotastrain R595. Theb«a gel-to-liquid crystalline phase transition behavior of the hydrocarbon chains withTc¼30Cfor MfGl-II as well as for LPS exhibits high similarity between the two glycolipids. A lipopolysaccharide-binding protein (LBP)-mediated incorporation into negatively charged liposomes is observed for both glycolipids. ...

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