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Báo cáo khoa học: Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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a-Helical integral-membrane proteins (IMPs) play a key role in many bio-logical processes, such as signal transduction, and are targets for 50% of current therapeutic drugs. In contrast to their significant abundance and biological importance, they comprise

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Nội dung Text: Báo cáo khoa học: Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses

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