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Báo cáo khoa học: Protein tyrosine phosphatases: regulatory mechanisms

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:17

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Protein-tyrosine phosphatases are tightly controlled by various mecha-nisms, ranging from differential expression in specific cell types to restricted subcellular localization, limited proteolysis, post-translational modifications affecting intrinsic catalytic activity, ligand binding and dimerization. Here, we review the regulatory mechanisms found to control the classical pro-tein-tyrosine phosphatases.

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