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Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec
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The tyrosine kinase expressed in hepatocellular carcinoma (Tec) is a non-receptor protein tyrosine kinase (PTK) that is expressed in hematopoietic cells, such as B and T lymphocytes, myeloid lineage cells and neutrophils. Mutations in the humanBtkgene cause X-linked agammaglobulinemia (XLA), but the corresponding mutation in mice results in a much milder defect.
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