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Báo cáo khóa học: NF-jB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

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The cytomegalovirus immediate-early (CMV IE) gene enhancer/promoter regulates the expression of immediate-early gene products and initiation of CMV replication. TNF-aand lipopolysaccharide (LPS) strongly activate the promoter, possibly involving NF-jB. CpG-oligodeoxy-nucleotides (CpG-ODNs), which contain unmethylated CpG dinucleotides in the context of particular base sequences, havegainedattentionbecauseof their stimulating effects, via NF-jB, which have a strong innate immune response.

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Nội dung Text: Báo cáo khóa học: NF-jB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene

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