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Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2
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Previously, we have shown by sensitivity analysis, that the oscillatory behavior of nuclear factor (NF-jB) is coupled to free IkappaB kinase-2 (IKK2) and IkappaBalpha(IjBa), and that the phosphorylation of IjBaby IKK influences the amplitude of NF-jB oscillations.
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