Báo cáo khoa học: Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica
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(S)-Stylopine is an important intermediate in the biosynthesis of benzophe-nanthridine alkaloids, such as sanguinarine. Stylopine biosynthesis involves the sequential formation of two methylenedioxy bridges. Although the methylenedioxy bridge-forming P450 (CYP719) involved in berberine bio-synthesis has been cloned from Coptis japonica[Ikezawa N, Tanaka M,
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