Báo cáo khoa học: Regulation of cathepsin B activity by 2A2 monoclonal antibody
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Cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease with both endo-peptidase and exopeptidase activity. The former is associated with the deg-radation of the extracellular matrix proteins, which is a process required for tumour cell invasion and metastasis. In the present study, we show that 2A2 monoclonal antibody, raised by our group, is able to regulate cathep-sin B activity.
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