Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain
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Nitric oxide synthases belong to a family of dual-flavin enzymes that trans-fer electrons from NAD(P)H to a variety of heme protein acceptors. Dur-ing catalysis, their FMN subdomain plays a central role by acting as both an electron acceptor (receiving electrons from FAD) and an electron donor, and is thought to undergo large conformational movements and engage in two distinct protein–protein interactions in the process.
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