Báo cáo khoa học: Structure and positioning comparison of two variants of penetratin in two different membrane mimicking systems by NMR
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The Antennapedia homeodomain protein ofDrosophilahas the ability to penetrate biological membranes and the third helix of this protein, residues 43–58, known as penetratin (RQIKIWFQNRRMKWKK-amide) has the same trans-locating properties as the entire protein. The variant, RQI KIFFQNRRMKFKK-amide, here called penetratin (W48F,W56F) does not have the same ability.
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