Báo cáo khoa học: The active essential CFNS3d protein complex A new perspective for the structural and kinetic characterization of the NS2B–NS3pro complex of dengue virus
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The NS2B–NS3 protease complex is essential for the replication of dengue virus, which is the etiologic agent of dengue and hemorrhagic fevers, dis-eases that are a burden for the tropical and subtropical areas of the world. The active form of the NS3 protease linked to the 40 residues of the NS2B cofactor shows highly flexible and disordered region(s)...
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