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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene
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Streptomyces coelicolorandStreptomyces pilosusproduce desferrioxamine siderophores which are encoded by thedesABCDgene cluster.S. pilosusis used for the production of desferrioxamine B which is utilized in human medicine. We report the deletion of thedesA gene encoding a lysine decarboxylase in Streptomyces coelicolorA3(2).
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