Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform
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In mouse, at least two catalytically active splice variants (mSMOaand mSMOl) of the flavin-containing spermine oxidase enzyme are present. We have demonstrated previously that the cytosolic mSMOais the major iso-form, while the mSMOlenzyme is present in both nuclear and cytoplasmic compartments and has an extra protein domain corresponding to the addi-tional exon VIa.
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