Báo cáo Y học: Molecular characterization of MRG19 of Saccharomyces cerevisiae Implication in the regulation of galactose and nonfermentable carbon source utilization
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We have reportedpreviously thatmultiple copies ofMRG19 suppressGALgenes inawild-typebut not inagal80strainof Saccharomyces cerevisiae. In this report we show that dis-ruption ofMRG19leads to a decrease in GALinduction whenS. cerevisiaeis inducedwith 0.02% but not with 2.0% galactose. Disruption ofMRG19in agal3background (this strainshows long-termadaptationphenotype)furtherdelays theGALinduction, supporting the notion that its function is important only under low inducing signals.
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