Báo cáo Y học: Proliferating cell nuclear antigen from a basidiomycete, Coprinus cinereus Alternative truncation and expression at meiosis
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The primary purpose of the present study was to investi-gate whether DNA replication at meiotic prophase also requires replication factors, especially proliferating cell nuclear antigen (PCNA). We cloned PCNA cDNAs (CoPCNA) from a cDNA library made from basidia of the basidiomycete,Coprinus cinereus. Interestingly, although CoPCNAis a single-copy gene in the genome, two dier-entPCNAcDNA species were isolated using degenerate primers and a meiotic cDNA library, and were designated asCoPCNA-aandCoPCNA-b. ...
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