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Báo cáo Y học: The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B
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Wehave examined the effectsof three ring-sizeanalogsof the cyclicb-sheet antimicrobial peptidegramicidinS (GS) on the thermotropic phase behavior and permeability of phos-pholipid model membranes and on the growth of the cell wall-less Gram-positive bacteriaAcholeplasma laidlawiiB. These three analogs have ring sizes of 10 (GS10), 12 (GS12) or 14 (GS14) amino acids, respectively.
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