Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 16)
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PNH has about the same frequency in men and women, and it is encountered in all populations throughout the world, but it is a rare disease: its prevalence is 1–5 per million (it may be somewhat less rare in Southeast Asia and in the Far East). There is no evidence of inherited susceptibility. PNH has never been reported as a congenital disease, but it can present in small children or in people in their seventies, although most patients are young adults. Clinical Features The patient may seek medical attention because one morning she or he has passed "blood instead of urine."...
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