Expression analysis of centrin gene in promastigote and amastigote forms of leishmania infantum iranian isolates: A promising target for live attenuated vaccine development against canine leishmaniasis

Leishmania parasites express various essential proteins in different growth phases (logarithmic/ stationary) and forms (promastigote/amastigote). Targeting the genes encoding such proteins paves the way for controlling these parasites. Centrin is an essential gene, which its protein product seems to be vital for the proliferation of Leishmania parasites.