Genotoxic potential of Cynanchum sarcomedium Meve & Liede coupled with its modulatory action on oxidative-stress–mediated genotoxicity by hydrogen peroxide

The present study evaluated the genotoxic effect of aqueous extract of C. sarcomedium Meve & Liede and its protective role in chromosomal aberrations induced by 2% hydrogen peroxide (H2O2) on Allium cepa root meristem. Our results showed that the C. sarcomedium extract induced major chromosomal aberrations, viz., nuclear lesions, chromosome breaks, chromosome laggards, vagrance, stickiness, and bridges.