Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress
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Although some molecularly targeted drugs for colorectal cancer are used clinically and contribute to a better prognosis, the current median survival of advanced colorectal cancer patients is not sufficient. Autophagy, a basic cell survival mechanism mediated by recycling of cellular amino acids, plays an important role in cancer.
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