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Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas
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The “HER2-low” nomenclature identifies breast carcinomas (BCs) displaying a HER2 score of 1+/2+ in immunohistochemistry and lacking ERBB2 amplification. Whether HER2-low BCs (HLBCs) constitute a distinct entity is debated.
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