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It takes 2 antioxidants to tango: The interaction between manganese superoxide dismutase and glutathione peroxidase-1
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Reactive oxygen species (ROS) are generated during mitochondrial oxidative metabolism. Accumulation of ROS without an effective antioxidant response can lead to oxidative stress, resulting in macromolecular damage that is implicated in the etiology of various diseases including cancer.
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