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KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer
Chia sẻ: ViPutrajaya2711 ViPutrajaya2711 | Ngày: | Loại File: PDF | Số trang:16
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The GTPase KRas4B has been utilized as a principal target in the development of anticancer drugs. PDE6δ transports KRas4B to the plasma membrane, where it is released to activate various signaling pathways required for the initiation and maintenance of cancer.
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