Low-depth genotyping-by-sequencing (GBS) in a bovine population: Strategies to maximize the selection of high quality genotypes and the accuracy of imputation

Genotyping-by-sequencing (GBS) has emerged as a powerful and cost-effective approach for discovering and genotyping single-nucleotide polymorphisms. The GBS technique was largely used in crop species where its low sequence coverage is not a drawback for calling genotypes because inbred lines are almost homozygous.