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Synthesis of E-stilbene azomethines as potent antimicrobial and antioxidant agents

Chia sẻ: Tử Dịch Quân Nguyệt | Ngày: | Loại File: PDF | Số trang:16

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A series of new extensively conjugated E -stilbene azomethines (5a–5h) were synthesized and screened for their antioxidant and antimicrobial activity. The compounds were tested against bacterial (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Bacillus subtilis) and fungal strains (Aspergillus niger, A. flavus, and Trichoderma harzianum) using the agar well diffusion method. Among the tested compounds, N ’-(4-nitrobenzylidene)- 2-((E)-styryl)benzohydrazide (5g) was found to possess potent antimicrobial activity higher than some drugs with significant activity reported in the literature, e.g., cefradine and terbinafine hydrochloride.

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Nội dung Text: Synthesis of E-stilbene azomethines as potent antimicrobial and antioxidant agents

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