To evaluate the stability of Carbopol 934 based transdermal gel of paracetamol nanocapsules

The nanocapsules were prepared by the interfacial deposition technique proposed in the year 1989. The required quantity of the drug and benzyl benzoate were mixed and added dropwise in the organic phase containing the polymer PLGA dissolved in the two organic solvents. With continuous stirring at 4000rpm for 1 hour, soyalecithin was added in the above mixture. Finally, the later was added in the solution of Polaxamer 188 with a continuous stirring speed of 4000rpm for 30 minutes.