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Albino rats
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The status of chromium as an essential nutrient is an ongoing debate despite its widespread use as supplement. Chromium supplement has been reported to improve glucose tolerance, insulin action and promote weight loss. This study examined the effect of given high concentrations of glucose D to chromium picolinate pretreated rats.
4p
viisac
23-09-2023
6
1
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In view of the toxic effects of theobromine and the medicinal potentials of Vernonia amygdalina, the present study therefore evaluated the effect of ethanol leaf extract of Vernonia amygdalina on the heart, liver and kidney of theobromine intoxicated male albino rats.
9p
viisac
23-09-2023
4
1
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The renal function plays a leading role in long-term control of arterial pressure. The comparative analysis of renal cortex transcriptome in ISIAH rats with inherited stress-induced arterial hypertension and normotensive WAG rats was performed using RNA-Seq approach.
14p
vinarcissa
21-03-2023
5
1
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Gentamicin (GM) is a low-cost, low-resistance antibiotic commonly used to treat gram-negative bacterial diseases. Cisplatin (Csp) is a platinum-derived anti-neoplastic agent. This experiment aimed to identify the early signs of gentamicin and cisplatin-induced nephrotoxicity in rats.
9p
vidarwin
22-02-2022
12
1
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It has been demonstrated that administration of exogenous ketone supplement ketone salt (KS) and ketone ester (KE) increased blood ketone level and delayed the onset of isoflurane-induced anesthesia in different rodent models, such as Wistar Albino Glaxo Rijswijk (WAG/Rij) rats. The modulatory effect of adenosinergic system may have a role in the ketone supplementation-evoked effects on isoflurane-generated anesthesia.
11p
vizhangzhidong
29-12-2021
5
0
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In this study, protective effects of lithium borate (LTB) on spermatogenesis as well as histopathological and immunohistochemical findings of testes in experimentally induced acute Cadmium (Cd) toxicity in rats were determined. Twenty-eight male Wistar albino rats, were used, weighing 200–220 g. Rats were randomly divided into 4 groups: Control, Cd, LTB, and LTB + Cd. Rats were anesthetized with ketamine at the end of the sixth day, blood was taken from their hearts, and the rats were decapitated. Typically, the control and LTB groups exhibited similar values.
11p
dolomite36
30-12-2021
9
0
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The aim of the present study was to clarify the effects of silymarin on experimental testicular ischemia / reperfusion injury. A total of 40 Wistar albino rats (10–12 weeks of age, weighing 280–300 g) were randomly divided into five groups. Control group: No surgical procedures were performed. Torsion 3 h / detorsion 3 h group; torsion 3 h / detorsion 24 h group; torsion 3 h / detorsion 3 h + silymarin (250 mg/kg) group; and torsion 3 h / detorsion 24 h + silymarin (250 mg/kg) group. In the study, 720° torsion was applied to the left testicle.
10p
dolomite36
30-12-2021
13
0
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The abnormalities, which was shown on liver status of hyperlipidemic rats were ameliorated by administration of POS preparations significantly. Liver histology showed significant improvement after treating hyperlipidemic rats by POS form compared with hyperlipidemic control.
14p
schindler
30-12-2021
12
0
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Anti-oxidative stress characters of extract was evaluated in liver and kidney antioxidant enzyme activities; catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase and glutathione peroxidase which were magnified in parallel with remarkable elevation on glutathione concentration comparable with diabetic control.
13p
schindler
30-12-2021
9
0
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N-acetylcysteine amide (NACA) is a new antioxidant molecule with powerful radical scavenging properties. The aim of this study was to investigate neuroprotective effects of NACA against paraquat (PQ) toxicity in the midbrains of rats by using motor coordination tests and biochemical and histological analysis. Thirty adult Wistar albino rats were divided into three groups: Group 1: control (n = 10), Group 2: PQ (10 mg/kg) (n = 10), and Group 3: PQ (10 mg/kg) + NACA (100 mg/kg) (n = 10). NACA was administrated intraperitoneally 30 min before PQ injection.
11p
tudichquannguyet
29-11-2021
6
1
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The medicinal plants combine three properties – curative, preventive and nutritive which provide the human body with necessary strength and vigour to cope with the disease and facilitate the action of the curative agents in the herbal drug. The major prevalent killers of India are cancer, diabetes, heart and liver diseases (Debnath et al., 2015).
290p
spiritedaway36
26-11-2021
10
2
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The effect of aged garlic extract on different haematological parameters was studied. The study included 72 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group. To group II high fat diet control was given as diet control. Rats in the group III were administered aged garlic extract at 200mg/kg bw. Group IV rats were administered aged garlic extract at 200mg/kg.bw with high fat diet. Rats in group V were administered atorvastatin at15mg/kg.bw with high fat diet.
10p
chauchaungayxua10
19-03-2021
17
1
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This work was done to demonstrate the effect of peripheral blood mononuclear cells on skeletal muscle regeneration after induced ischemia /reperfusion injury.
12p
chauchaungayxua10
19-03-2021
12
1
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The aim of this study was to assess the effect of oral ingestion of honey as an adjuvant therapy in acute ingestion of potassium hydroxide in adult male albino rats.
14p
trinhthamhodang1216
19-11-2020
11
2
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The present study was designed to evaluate the role of umbelliferone in alleviating hyperlipidemia and oxidative damage in streptozotocin induced diabetes mellitus in wistar albino rats. Six groups of rats were used as control, diabetic control, umbelliferone at 20 mg/kg b.wt., umbelliferone at 40 mg/kg b.wt. and combination of glibenclamide and umbelliferone at 20 mg/kg b. wt., was used in the study.
13p
trinhthamhodang1216
19-11-2020
12
0
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Hence the objective of this study was to assess the reproductive toxicity in male albino Wistar rats induced by doxorubicin and ameliorative effect of quercetin to overcome the doxorubicin induced testicular toxicity.
12p
nguaconbaynhay8
13-10-2020
8
2
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The present study was aim to evaluate the time-dependent wound healing effects of curcumin ointment (0.3%) in excision wound model in albino rats. Thirty six acclimatized rats were equally divided into two groups and ~2×2 cm2 open excision-type wound was created in rats in Group I (control) and Group II (treated).
11p
chauchaungayxua8
03-10-2020
28
1
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The present study aimed to investigate the protective effect of Clerodendrum infortunatum (CI) by targeting its antioxidant properties against liver damage induced by arsenic in rats. Total 18 rats weighting 140-200 g, were divided into three groups. Groups representing control and treatment groups [treated with sodium arsenite alone (3 mg/kg b.w. of rats) and in combination with methanolic extract of CI leaves (100 mg/kg b. w.)]; groups named I, II and III respectively. Sodium arsenite and CI extracts were administered orally, once daily over a period of 28 days. Body wt.
9p
cothumenhmong7
09-09-2020
9
1
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Cisplatin (CP) is considered one of the most effective and widely used anti-neoplastic drug in the treatment of different solid organ tumors. The present study was carried out to assess the hematological changes following CP administration in Wistar albino rats and its amelioration by extract of Andrographis paniculata (AP). The study included 60 Wistar albino rats were divided into 12 rats in each group. Group I served as normal control group.
8p
angicungduoc6
22-07-2020
8
1
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This study was carried out to evaluate the effect of fenugreek plant on CCL4 –induced liver injury by following the hematological and biochemical parameters. To achieve this purpose forty male albino rats were used and divided to four groups. The first group represented control group which received normal diet and intraperitoneal injection with oil (0.5ml/kg). The second group represented the CCL (1ml/kg) model. The third group received 200 mg/kg fenugreek leaves extract by gavage.
10p
angicungduoc6
20-07-2020
10
1
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