Bacterial infections

Bacterial meningitis is an acute central nervous infection with high mortality or permanent neurological sequelae if remained undiagnosed. The present study will therefore aim to set up in-house PCR assays for diagnosis of six pathogens causing the disease including H. influenzae type b, S. pneumoniae, N. meningitidis, S. suis serotype 2, E. coli and S. aureus.

7p vifaye 20-09-2024 2 1   Download

Bacterial infections have a substantial impact on global health and can become serious if misdiagnosed with several diseases related to the central nervous, cardiovascular, and respiratory systems. The prognosis in patients with infectious disease strongly depends on early diagnosis and appropriate antibiotic therapy.

8p vifaye 20-09-2024 3 1   Download

Periodontitis is a chronic bacterial infection destroying tooth-supporting tissues. Like metronidazole, tinidazole (TNZ) is also effective in treating periodontitis. The preparation of polymeric nanoparticles containing TNZ helps to improve the solubility and increase the bioavailability of the drug. Objectives: This study aimed to formulate and optimize TNZ nanoparticles and evaluate their physicochemical properties.

9p vifaye 20-09-2024 3 1   Download

This study aims to evaluate the microbial contamination level and identify bacterial colonization of the operating room in the hospital. Methods: Three sampling procedures were used in this study, which includes swabbing, air sampler and contact agar plate. Collected samples from 8 ORs were transported and microbiologically processed using standard procedures. Bacteria were identified by morphological, biochemical tests and Vitek 2 Compact system.

6p vinatisu 29-08-2024 7 0   Download

This study addresses the elevated prevalence of skin and soft tissue infections (SSTIs) within the pediatric demographic, necessitating a comprehensive inquiry into their varied clinical manifestations. The primary objectives involve the assessment of clinical and laboratory characteristics of SSTIs in children and an exploration of their correlation with treatment efficacy.

5p vinatisu 29-08-2024 0 0   Download

Severe congenital neutropenia (SCN) is an exceptionally rare genetic disorder associated with life-threatening bacterial infections. Among the several genetic variations related to SCN, heterozygous mutations in the ELANE gene encoding neutrophil elastase account for approximately 40 - 55% of the genetic causes.

6p vinatisu 29-08-2024 4 1   Download

The objective was to assess the distribution of urinary tract bacterial pathogens and to determine the antibiotic susceptibility profile of the isolates in our setting. Single positive cultures with a colony count of >105 CFU on CLED medium were identified and their antibiotic sensitivity and resistance profile was depicted in the form of an antibiogram.

7p gaocaolon9 22-12-2020 18 3   Download

75% of the mortality associated with burn injuries is related to infection The aim of the present study was to identify the bacterial profile of burn wound infection (BWI) in our setting and determine their susceptibility pattern to commonly used antibiotics.This prospective study was conducted over a period of one year in a teaching tertiary care hospital, Chennai. A total of 100 patients with burns of total body surface area (TBSA) of 20% to 40% were included. Three wound swabs on 1st , 4 th and 7th day were collected aseptically and processed.

9p kequaidan7 01-09-2020 17 3   Download

This topic is researched for two goals: Description of clinical characteristics, subclinical disease Peritonitis infections spontaneously. Results of identification of bacteria and antibiotics on the isolates of bacteria. Evaluation of the results of treatment of peritonitis infection spontaneously in patients with cirrhosis.

27p slimzslimz 21-12-2019 37 8   Download

This study was done to assess the incidence of urinary tract infection (UTI) in children from 2 months to 6 years old in some areas of Haiphong Vietnam, and bacterial causes and their antibiotic sensitivity on antibiogram from July to October 2007. Method: This was a cross-sectional study including the screening of clean voiding midstream samples in the morning for UTI.

8p thiendiadaodien_9 04-03-2019 25 3   Download

Chapter 8 - Major shifts in bacterial transcription. In this chapter, students will be able to understand: Sigma factor switching, the RNA polymerase encoded in phage T7, infection of E. coli by phage λ,...and another contents.

40p tangtuy05 30-03-2016 51 4   Download

Xanthomonas campestrispv.vitians is a Gram-negative plant-associated bacterium that acts as causative agent of bacterial leaf spot and headrot in lettuce. The lipopolysac-charide of this bacterium is suspected to be an important molecule for adhesion to and infection of the plants. The lipopolysaccharide has been isolated from the phenol phase and the O-specific chain characterized by compositional analysis, high fieldNMRandMALDI-TOFMS.

9p research12 23-04-2013 45 2   Download

Drosophilais a powerful model system to study the regula-tory and effector mechanisms of innate immunity. To iden-tify molecules induced in the course of viral infection in this insect, we have developed a model based on intrathoracic injection of the picorna-like DrosophilaCvirus(DCV).We have used MALDI-TOF mass spectrometry to compare the hemolymph of DCV infected flies and control flies. By contrast with the strong humoral response triggered by injectionof bacteriaor fungal spores, we have identifiedonly one molecule induced in the hemolymph of virus infected flies....

10p tumor12 20-04-2013 27 3   Download

Highly active, small-molecule furin inhibitors are attractive drug candidates to fend off bacterial exotoxins and viral infection. Based on the 22-residue, active Lys fragment of the mung bean trypsin inhibitor, a series of furin inhibitors were designed and synthesized, and their inhibitory activity towards furin and kexin was evaluated using enzyme kinetic analysis.

8p inspiron33 25-03-2013 48 5   Download

Bacterial infections at epithelial surfaces, such as those that line the gut and the lung, stimulate the migration of neutrophils through the co-ordi-nated actions of chemoattractants secreted from pathogen-stimulated epi-thelial cells. One such factor involved in attracting polymorphonuclear leukocytes across the epithelium and into the lumen has until recently remained elusive.

6p galaxyss3 21-03-2013 38 3   Download

The incidence of mixed viral⁄bacterial infections has increased recently because of the dramatic increase in antibiotic-resistant strains, the emer-gence of new pathogens, and the resurgence of old ones. Despite the relat-ively well-known role of viruses in enhancing bacterial infections, the impact of bacterial infections on viral infections remains unknown.

14p galaxyss3 19-03-2013 37 3   Download

Type III secretion systems of Gram-negative pathogenic bacteria allow the injection of effector proteins into the cytosol of host eukaryotic cells. Cros-sing of the eukaryotic plasma membrane is facilitated by a translocon, an oligomeric structure made up of two bacterial proteins inserted into the host membrane during infection.

10p galaxyss3 19-03-2013 36 4   Download

EspB is a multifunctional protein associated with the type III secretion system of enterohaemorrhagic Escherichia coli, and interacts with various biomolecules includinga-catenin in the host cell. The binding of EspB to a-catenin is thought be involved in actin reorganization during bacterial infection, although the precise mechanism of this phenomenon is still unclear.

8p vinaphone15 28-02-2013 27 4   Download

Mycobacterium tuberculosisis the causative agent of human tuberculosis (TB). Mycobacterial secretory protein ESAT-6 induces matrix metallopro-teinase (MMP)-9 in epithelial cells neighboring infected macrophages. MMP-9 then enhances recruitment of uninfected macrophages, which con-tribute to nascent granuloma maturation and bacterial growth.

10p cosis54 09-12-2012 39 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection

11p dauphong4 24-12-2011 44 5   Download