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Biomarker detection
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The aim of this study was to summarize the diagnostic performance of circulation EV RNAs and EV proteins for CRC detection and to understand the diagnostic value of EV miRNAs in different circulation specimens.
14p
vishanshan
27-06-2024
1
1
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We aimed to screen novel gene signatures for ovarian cancer (OC) and explore the role of biomarkers in OC via regulating pyroptosis using bioinformatics analysis. The proliferation, migration, and invasion were determined using cell counting kit and transwell assay. Enzyme-linked immunosorbent assay was applied to measure infammatory factors. The mRNA and protein expression were detected using real-time quantitative PCR and western blot.
15p
vishanshan
27-06-2024
1
1
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The present study aims to investigate the dynamic of plasma EVs in meningioma patients during radiotherapy and subsequent follow-up, which may serve as biomarker in treatment response and disease monitoring (e.g. early detection of relapse).
6p
vishanshan
27-06-2024
2
1
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Despite recent improvements in cancer detection and survival rates, managing cancer-related pain remains a significant challenge. The objective of this work was to select a panel of biomarkers of central pain processing and modulation and assess their ability to predict chronic pain in patients with cancer using predictive artificial intelligence (AI) algorithms.
11p
vikoch
27-06-2024
1
1
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Breast cancer remains a significant health challenge worldwide, necessitating the identification of reliable biomarkers for early detection, accurate prognosis, and targeted therapy.
13p
vikoch
27-06-2024
1
1
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Summary of tumor-produced circulating proteins as biomarkers in breast cancer (BC) detection. Subjects and method: A meta-analysis of 50 researches on protein biomarkers in BC diagnosis.
6p
viohoyo
02-04-2024
3
2
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The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes hypothesized as one mechanism by which both genetic and non-genetic variation influence gene regulation and pathogenesis. The aim of this study was to identify DNA methylation biomarkers of ASD detectable at birth.
13p
vibransone
28-03-2024
2
2
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Circular RNAs (circRNAs) are 3′–5′ covalently closed RNA rings produced from back-splicing of precursor mRNA in eukaryotes. Recent studies, using both computational and experimental approaches, have allowed advanced characterization of circRNAs, leading the research field into a new era and shedding light on the contribution of circRNAs to disease.
3p
vibransone
28-03-2024
1
1
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Profiling the somatic mutations of genes which may inform about tumor evolution, prognostics and treatment is becoming a standard tool in clinical oncology. Commercially available cancer gene panels rely on manually gathered cancer-related genes, in a “one-size-fits-many” solution.
9p
vioraclene
31-03-2024
3
2
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Obesity and type 2 diabetes (T2D) are linked both with host genetics and with environmental factors, including dysbioses of the gut microbiota. However, it is unclear whether these microbial changes precede disease onset.
14p
vioraclene
31-03-2024
4
2
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Pancreatic cancer is an aggressive cancer with dismal prognosis, urgently necessitating better biomarkers to improve therapeutic options and early diagnosis. Traditional approaches of biomarker detection that consider only one aspect of the biological continuum like gene expression alone are limited in their scope and lack robustness in identifying the key regulators of the disease.
20p
vioraclene
31-03-2024
5
1
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Most two-group statistical tests find broad patterns such as overall shifts in mean, median, or variance. These tests may not have enough power to detect effects in a small subset of samples, e.g., a drug that works well only on a few patients.
19p
vibransone
28-03-2024
4
1
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Ebook "Practical gas chromatography: A comprehensive reference" continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors.
904p
tudohanhtau1006
29-03-2024
7
1
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Ebook "Analysis of samples of clinical and alimentary interest with paper-based devices" presents two main sets of paper-based analytical systems. The first set is a platform for the analysis of glucose, cholesterol and uric acid in biological samples, and the second set is a cutting-edge electronic tongue system for the analysis of beverages (mineral water, beer, wine). This thesis also provides an extensive review of 33 methods of enzyme immobilization on paper which have been evaluated to enhance the storage stability of the proposed system for biomarker detection.
200p
lamquandat
28-12-2023
9
2
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Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methylation is an early epigenetic event in the development of BCa. The aim of this study was to identify methylation biomarkers for early detection of BCa.
9p
vileonardodavinci
23-12-2023
6
3
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Early detection of pancreatic ductal adenocarcinoma (PDAC) is essential for survival. Preliminary research demonstrated significant associations between structural alternation of mycobiota and PDAC. In this study, we investigated the associations between oral mycobiota and PDAC. We further explored mycobiota biomarkers for PDAC detection.
13p
vileonardodavinci
23-12-2023
3
2
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The increasing prevalence of cancer detection necessitated practical strategies to deliver highly accurate, beneficial, and dependable processed information together with experimental results. We deleted the cancer biomarker NOX4 using three novel genetic knockout (KO) methods. Homology-directed repair (HDR), Dual allele HITI (Du-HITI) and CRISPR-excision were utilized in this study.
15p
vileonardodavinci
23-12-2023
5
3
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Overall survival of advanced colorectal cancer (CRC) patients remains poor, and gene expression analysis could potentially complement detection of clinically relevant mutations to personalize CRC treatments.
19p
vileonardodavinci
23-12-2023
4
3
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To evaluate the diagnostic value of adding human epididymis protein 4 (HE4), cancer antigen 125 (CA125) and risk of malignancy algorithm (ROMA) to ultrasound for detecting ovarian cancer in patients with a pelvic mass.
11p
vileonardodavinci
23-12-2023
8
4
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The aim of this work was to screen and validate biomarkers of ovarian cancer-initiating cells to detect the mechanisms of recurrence of epithelial ovarian cancer (EOC). Methods: Stably labelled the amino acid in side population (SP) cells of epithelial ovarian cancer which were rich in cancer-initiating cells and non-SP cells with isotope in culture and differentially expressed cellular membrane proteins in SP cells were identified through proteomics technology.
15p
vialfrednobel
23-12-2023
5
3
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