Gastric carcinoma

Lymph node metastasis (LNM) status is an important prognostic factor that strongly influences the treatment decision of early gastric cancer (EGC). This study aimed to evaluate the pattern and clinical significance of LNM in EGC. Methods: A total of 354 patients with carcinoma in situ (n =42), EGC (n =312) who underwent radical gastrectomy were enrolled. Their clinicopathological features, pathological reports, and prognostic data were collected and analyzed.

13p vielonmusk 21-01-2022 13 1   Download

Survival times differ among patients with advanced gastric carcinoma. A precise and universal prognostic evaluation strategy has not yet been established. The current study aimed to construct a prognostic scoring model for mortality risk stratification in patients with advanced gastric carcinoma.

13p vielonmusk 21-01-2022 14 1   Download

Adecrease in the level ofO-acetylatedsialicacidsobserved in colorectal carcinoma may lead to an increase in the expres-sion of sialyl Lewis X , a tumor-associated antigen, which is related toprogressionof colorectal cancer tometastasis. The underlyingmechanism for this reduction is, however, not fully understood. Two enzymes are thought to be primarily responsible for the turnover of O-acetyl ester groups on sialic acids; sialate-O-acetyltransferase (OAT) and sialate-O-acetylesterase (OAE).

10p dell39 03-04-2013 64 5   Download

Angiogenic switch in renal cell carcinoma (RCC) is attributed to the inactivation of the von Hippel–Lindau tumor suppressor, stabilization of hypoxia inducible factor-1 transcription factor and increased vascular endothelial growth factor.

13p media19 05-03-2013 26 1   Download

Tumor protein D52 (TPD52) is a protein found to be overexpressed in prostate and breast cancer due to gene amplification. However, its physio-logical function remains under investigation. In the present study, we inves-tigated the response of the LNCaP human prostate carcinoma cell line to deregulation of TPD52 expression.

11p vinaphone15 28-02-2013 41 1   Download

Cellular prion protein (PrP C ), a glycosyl-phosphatidylinositol-anchored membrane protein with unclear physiological function, was previous found to be upregulated in adriamycin (ADR)-resistant gastric carcinoma cell line SGC7901/ADR compared to its parental cell line SGC7901.

10p vinaphone15 27-02-2013 43 2   Download

The tyrosine kinase expressed in hepatocellular carcinoma (Tec) is a non-receptor protein tyrosine kinase (PTK) that is expressed in hematopoietic cells, such as B and T lymphocytes, myeloid lineage cells and neutrophils. Mutations in the humanBtkgene cause X-linked agammaglobulinemia (XLA), but the corresponding mutation in mice results in a much milder defect.

11p viettel02 20-02-2013 31 3   Download

MicroRNAs are an evolutionarily conserved class of endogenous noncod-ing RNAs that modulate gene expression at the post-transcriptional level. Recently, microRNA-23a (miR-23a) has been found to function as a growth-promoting and antiapoptotic factor in hepatocellular carcinoma cells.

9p viettel02 19-02-2013 22 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine

13p dauphong6 05-01-2012 52 6   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sequence analysis of the Epstein-Barr virus (EBV) BRLF1 gene in nasopharyngeal and gastric carcinomas

8p dauphong2 23-12-2011 47 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Primary gastric adenosquamous carcinoma in a Caucasian woman: a case report

5p toshiba25 09-12-2011 36 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Adhesions due to peritoneal carcinomatosis caused by a renal carcinoma leading to mechanical gastric outlet obstruction: a case report...

4p thulanh25 07-12-2011 48 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Aquaporin-3 positively regulates matrix metalloproteinases via PI3K/AKT signal pathway in human gastric carcinoma SGC7901 cells

6p toshiba22 21-11-2011 72 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Gastric metastases originating from occult breast lobular carcinoma: diagnostic and therapeutic problems

6p matuot_238 13-10-2011 49 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The efficacy of preoperative PET/CT for prediction of curability in surgery for locally advanced gastric carcinoma

7p matuot_238 12-10-2011 59 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma

8p hoami_238 11-10-2011 60 4   Download

Bệnh nhân này đàn ông, gốc Trung Mỹ, cách đây 6 năm (khi 59 tuổi) than đau bụng, chữa thuốc trong 3 tháng không khỏi, Endoscopy (EGD) cho thấy loét bao tử 1.6 cm X 0.8 cm, nhưng bờ loét gồ ghề chứ không nhẵn: biopsy cho thấy adenocarcinoma. Surgeon làm partial gastrectomy. Pathology cho thấy ung thư thấm nhập suốt vách của bao tử đến serosa, vào lymphatics vessels, nhưng lymph nodes negative for metastases. Sau đó gửi sang medical oncology hỏi ý kiến còn phái làm gì nữa. Work up (Xét nghiệm thêm nữa) về metastases cho...

8p sinhtobo111 13-04-2011 45 3   Download

Management of Disseminated CUP Patients who present with liver, brain, and adrenal metastatic disease usually have a poor prognosis. Beside primary peritoneal carcinoma, carcinomatosis presenting as CUP in other settings is not uncommon. Gastric, appendicular, colon, pancreas, and cholangiocarcinoma are all possible primaries, and imaging, endoscopy, and pathologic data help in the evaluation. Traditionally, platinum-based combination chemotherapy regimens have been used to treat patients with CUP.

6p thanhongan 07-12-2010 71 5   Download

Bibliography ESOPHAGEAL CANCER Al-Sarraf M et al: Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: An intergroup study. J Clin Oncol 15:277, 1997 [PMID: 8996153] Bedenne L et al: Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102.

19p konheokonmummim 03-12-2010 83 4   Download

Gastric Adenocarcinoma: Treatment Complete surgical removal of the tumor with resection of adjacent lymph nodes offers the only chance for cure. However, this is possible in less than a third of patients. A subtotal gastrectomy is the treatment of choice for patients with distal carcinomas, while total or near-total gastrectomies are required for more proximal tumors. The inclusion of extended lymph node dissection in these procedures appears to confer an added risk for complications without enhancing survival.

5p konheokonmummim 03-12-2010 74 3   Download